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Department of Animal Science

College of Agriculture and Natural Resources

Dr. Wei Guo


Assistant Professor

Muscle Biology



B.S., 1999, College of Life Science, China Agriculture University, Beijing, China

Ph.D., 2004, Animal Science, China Agriculture University, Beijing, China


Professional experience:

2013.8-present:  Assistant Professor, University of Wyoming, Animal Science, Laramie, Wyoming

2013.1-2013.8: Sr. Scientist, University of Wisconsin-Madison, School of Medicine and Public Health, Cell and Regenerative Biology, Madison, Wisconsin

2011.1-2013.1: Sr. Scientist, International Biotechnology Center, Minitube of America, Inc., Verona, Wisconsin

2009.12-2011.1: Assistant Scientist, University of Wisconsin-Madison, College of Agriculture and Life Science, Madison, Wisconsin

2008.9-2009.12: Postdoctoral, University of Wisconsin-Madison, Nutritional Science, Madison, Wisconsin

2005.7-2008.9: Postdoctoral, University of Wisconsin-Madison, Animal Science, Madison, Wisconsin

2004.7-2005.7: Research Assistant Professor, Chinese Center for Disease Control and Prevention, Beijing, China


Research Interests:

Alternative splicing results in the biodiversity of proteins that can be encoded by the genome in eukaryotes, and approximately 95% of multi-exonic genes are alternatively spliced. For this reason, alternative splicing is tightly regulated in different tissues and developmental stages and its disruption can lead to a wide range of human and animal disorders. Muscle is one of the first tissues which undergoes alternative splicing. Muscle-specific alternative splicing is related to muscle development, function and diseases, but the splicing mechanism is far less understood. Therefore, my research aims to understand the molecular and cellular mechanisms underlying muscle development and regeneration, and heart diseases. Success in my proposed research will advance our understanding of the molecular basis of muscle regeneration and heart diseases, and foster the development of diagnostic and therapeutic strategies of heart diseases.



Muscle biology




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