Department of Molecular Biology
University of Wyoming
Ag C Bldg., Room 6007
Laramie, WY 82071
E-mail: gomelsky@uwyo.edu
Office: (307) 766-3522
Lab: (307) 766-3517
Fax: (307) 766-3875
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Hirsch index, h = 28; total citations: >2,900;
annual citation rate since 2007: ~300-400 (Google Scholar).
| 2010-2013 | 61 | Gomelsky, M. and J.H. Zeilstra-Ryalls. 2013. The living genome of a purple nonsulfur photosynthetic bacterium: Overview of the Rhodobacter sphaeroides transcriptome landscapes. Adv Botanical Res Special issue: Genome evolution of photosynthetic bacteria. (J.T. Beatty, ed.) (in press). |
| 60 | Römling, U., M.Y. Galperin and M. Gomelsky. 2012. Cyclic di-GMP: The first 25 years of a universal bacterial second messenger. Microbiol Mol Biol Rev (in press). | |
| 59 | Branchu, P., T, Hindré, X. Fang, R. Thomas, M. Gomelsky, L. Claret, J. Hareld, A.P. Gobert, and C. Martin. 2012. The c-di-GMP phosphodiesterase VmpA absent in Escherichia coli K12 strains affects motility and biofilm formation in the enterohemorrhagic O157:H7 serotype. Vet Immunol Immunopathol (in press). | |
| 58 | Hull, T.D., M.H. Ryu, M.J. Sullivan, N.T. Klena, R.C. Johnson, R.M. Geiger, M. Gomelsky, and J.A. Bennett. 2012. C-di-GMP phosphodiesterases RmdA and RmdB are involved in regulating colony morphology and development in Streptomyces coelicolor. J Bacteriol 194: 4642-4651. | |
| 57 | Gomelsky, M. 2012. C-di-GMP-mediated decisions in the surface-grown Vibrio parahaemolyticus: A different kind of motile-to-sessile transition. Commentary. J Bacteriol 194:911-913. | |
| 56 | Hobley, L., R.K.Y. Fung, M.A.T.S. Harris, J.M. Dabhi, S.S. King, C. Lambert, K. Uchida, S. Basford, R. Ahmad, S.I. Aizawa, M. Gomelsky, and R.E. Sockett. 2012. Discrete cyclic di-GMP-dependent control of bacterial predation versus axenic growth in Bdellovibrio bacteriovorus. PLoS Pathogens 8:e1002493. | |
| 55 | Monteiro, C., X. Fang, I. Ahmad, M. Gomelsky, and U. Römling. 2011. Regulation of biofilm components in Salmonella enterica serovar Typhimurium by lytic transglycosylases involved in cell wall turnover. J Bacteriol 193:6443-6451. | |
| 54 | Tsuzuki, M., O.V. Moskvin, M. Kuribayashi, K. Sato, S. Retamal, M. Abo, J. Zeilstra-Ryalls, and M. Gomelsky. 2011. Salt-stress induced changes in the transcriptome, compatible solutes and membrane lipids in the facultatively phototrophic bacterium Rhodobacter sphaeroides. Appl Environ Microbiol 77:7551-7559. | |
| 53 | Gomelsky, M. and W.H. Hoff. 2011. Light helps bacteria make important lifestyle decisions. Trends Microbiol 19:441-448. | |
| 52 | He, M., Z. Ouyang, B. Troxell, H. Xu, A. Moh, J. Piesman, M.V. Norgard, M. Gomelsky, and X.F. Yang. 2011. Cyclic di-GMP is essential for the survival of the Lyme disease spirochete in ticks. PLoS Pathogens 7:e1002133. | |
| 51 | Smith, A., M. Balazinska, C. Baru, M. Gomelsky, M. McLennan, L. Rose, B. Smith, E. Stewart, and E. Kolker. 2011. Biology and data-intensive science in the beginning of the 21st century. OMICS 15:209-212. | |
| 50 | Gomelsky, M. 2011. cAMP, c-di-GMP, c-di-AMP and now cGMP: Bacteria use them all! MicroCommentary. Mol Microbiol 79:562-565. | |
| 49 | Bobrov, A.G., O. Kirillina, D.A. Ryjenkov, C.M. Waters, P.A. Price, J.D. Fetherson, D. Mack, W.E. Goldman, M. Gomelsky and R.D. Perry. 2011. Systematic analysis of cyclic di-GMP signaling enzymes and their role in biofilm formation and virulence in Yersinia pestis. Mol Microbiol 79:533-551. (Faculty of 1000 Medicine: "Recommended") | |
| 48 | Moskvin, O.V., D. Bolotin, A. Wang, P.S. Ivanov and M. Gomelsky. 2011. Rhodobase, a meta-analytical tool for reconstructing gene regulatory networks in a model photosynthetic bacterium. BioSystems 103:125-131. | |
| 47 | Ryu, M.H., O.V. Moskvin, J. Siltberg-Liberles and M. Gomelsky. 2010. Natural and engineered photoactivated nucleotidyl cyclases for optogenetic applications. J Biol Chem 285: 41501-41508. (Faculty of 1000 Biology: "Recommended") | |
| 46 | Golomysova, A.N., M. Gomelsky and P.S. Ivanov. 2010. Flux balance analysis of the photoheterotrophic growth of Rhodobacter sphaeroides relevant to biohydrogen production. Intl J Hydrogen Energy 35:12751-12760. | |
| 45 | Moskvin, O.V., M.A. Gilles-Gonzalez and M. Gomelsky. 2010. The PpaA/AerR regulators of photosynthesis gene expression from anoxygenic phototrophic proteobacteria contain heme-binding SCHIC domains. J Bacteriol 192:5253-5256. | |
| 44 | Fang, X. and M. Gomelsky. 2010. A post-translational, c-di-GMP-dependent mechanism regulating bacterial flagellar motility. Mol Microbiol 76:1295-1305. (Faculty of 1000 Biology: "Recommended") | |
| 43 | Golomysova, A.N., M. Gomelsky and P.S. Ivanov. 2010. Mathematical modeling of bacterial metabolism. Moscow University Physics Bulletin 65:230-233. | |
| 2000-2009 | 42 | Gomelsky, M. 2009. The core pathway: diguanylate cyclases, phosphodiesterases, and c-di-GMP-binding proteins. Chapter 4, pp. 37-56. In The second messenger cyclic di-GMP. (A. Wolfe and K. Visick, eds.) ASM Press, Washington, DC. |
| 41 | Gomelsky, M. 2009. C-di-GMP-binding CRP-like protein: a spectacular new role for a veteran signal transduction actor. Commentary. J Bacteriol 191:6785-6787. | |
| 40 | Barends, T.R.M., E. Hartmann, J. Griese, T. Beitlich, N.V. Kirienko, D.A. Ryjenkov, J. Reinstein, R.L. Shoeman, M. Gomelsky |
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| 39 | Tyagi, A., A. Penzkofer, J. Griese, I. Schlichting, N.V. Kirienko, M. Gomelsky. 2008. Photodynamics of blue-light-regulated phosphodiesterase BlrP1 protein from Klebsiella pneumoniae and its photoreceptor BLUF domain. Chem Physics 354:130-141. | |
| 38 | Gomelsky, L., O.V. Moskvin, R. Stenzel, D. Jones, T.J. Donohue and M. Gomelsky. 2008. Hierarchical regulation of photosynthesis gene expression by oxygen-responsive PrrBA and AppA-PpsR systems of Rhodobacter sphaeroides. J Bacteriol 190:8106-8114. | |
| 37 | Holland, L.M., S.T. O'Donnell, D.A. Ryjenkov, L. Gomelsky, S.R. Slater, P.D. Fey, M. Gomelsky and J.P. O'Gara. 2008. A staphylococcal GGDEF domain protein regulates biofilm formation independently of c-di-GMP. J Bacteriol 190:5178-5189. | |
| 36 | Claret, L., S. Miquel, N. Vieille, D.A. Ryjenkov, M. Gomelsky and A. Darfeuille-Michaud. 2007. The flagellar sigma factor FliA regulates adherence and invasion of Crohn disease-associated Escherichia coli via a c-di-GMP-dependent pathway. J Biol Chem 282:33275-33283. (Faculty of 1000 Biology: "Recommended") | |
| 35 | Moskvin, O.V., S. Kaplan, M-A. Gilles-Gonzalez and M. Gomelsky. 2007. Novel heme-based oxygen sensor with a revealing evolutionary history. J Biol Chem 282:28740-28748. (Faculty of 1000 Biology: "Recommended") | |
| 34 | Zeller, T., M.A. Mraheil, O.V. Moskvin, K. Li, M. Gomelsky and G. Klug. 2007. Regulation of hydrogen peroxide-dependent gene expression in Rhodobacter sphaeroides: Regulatory functions of OxyR. J Bacteriol 189:3784-3792. | |
| 33 | Tarutina, M., D.A. Ryjenkov and M. Gomelsky. 2006. An unorthodox bacteriophytochrome from Rhodobacter sphaeroides involved in turnover of the second messenger c-di-GMP. J Biol Chem 281:34751-34758. | |
| 32 | Ryjenkov, D.A., R. Simm, U. Römling, and M. Gomelsky. 2006. The PilZ domain is a receptor for the second messenger c-di-GMP. The PilZ domain protein YcgR controls motility in enterobacteria. J Biol Chem 281:30310-30314. (Accelerated publication) | |
| 31 | Harpster, M.H., S. Bandyopadhyay, D. P. Thomas, P.S. Ivanov, J.A. Keele, N. Pinegina, B. Gao, V. Amarendran, M. Gomelsky, R.J. McCormick, and M.M. Stayton. 2006. Earliest changes in the left ventricular transcriptome postmyocardial infarction. Mammal Genome 17:701-715. | |
| 30 | Zeller, T., O.V. Moskvin, K. Li, G. Klug and M. Gomelsky. 2005. Transcriptome and physiological responses to hydrogen peroxide in the facultatively phototrophic bacterium Rhodobacter sphaeroides. J Bacteriol 187:7232-7242. | |
| 29 | Jung, A., T. Domratcheva, M. Tarutina, Q. Wu, W.-H. Ko, R.L. Shoeman, M. Gomelsky, K.H. Gardner and I. Schlichting. 2005. Structure of a bacterial BLUF photoreceptor: Insights into blue light-mediated signal transduction. Proc Natl Acad Sci USA 102:12350-12355. | |
| 28 | Galperin, M.Y. and M. Gomelsky. 2005. Bacterial signal transduction modules: From genOMICS to biology. Features. ASM News 71:326-333. | |
| 27 | Schmidt, A.J., D.A. Ryjenkov and M. Gomelsky. 2005. The ubiquitous protein domain EAL is a c-di-GMP-specific phosphodiesterase: Enzymatically active and inactive EAL domains. J Bacteriol 187:4774-4781. | |
| 26 | Römling, U., M. Gomelsky and M.Y. Galperin. 2005. C-di-GMP: the dawning of a novel bacterial signalling system. MicroReview. Mol Microbiol 57:629-639. | |
| 25 | Moskvin, O.V., L. Gomelsky and M. Gomelsky. 2005. Transcriptome analysis of the Rhodobacter sphaeroides PpsR regulon: PpsR as a master regulator of photosystem development. J Bacteriol 187:2148-2156. | |
| 24 | Ryjenkov, D.A., M. Tarutina, O.V. Moskvin and M. Gomelsky. 2005. Cyclic diguanylate is a ubiquitous signaling molecule in bacteria: Insights into the biochemistry of the GGDEF protein domain. J Bacteriol 187:1792-1798. | |
| 23 | Braatsch, S., O.V. Moskvin, G. Klug and M. Gomelsky. 2004. Responses of the Rhodobacter sphaeroides transcriptome to blue light under semiaerobic conditions. J Bacteriol 186:7726-7735. | |
| 22 | Pappas, C.T., J. Sram, O.V. Moskvin, P.S. Ivanov, R.C. Mackenzie, M. Choudhary, M.L. Land, F.W. Larimer, S. Kaplan and M. Gomelsky. 2004. Construction and validation of the genome-wide DNA microarray of Rhodobacter sphaeroides 2.4.1: Transcriptome flexibility at diverse growth modes. J Bacteriol 186:4748-4758. | |
| 21 | Li, S-Y., M. Gomelsky, J. Duan, Z. Zhang, L. Gomelsky, X. Zhang, P.N. Epstein and J. Ren. 2004. Overexpression of aldehyde dehydrogenase-2 (ALDH2) transgene prevents acetaldehyde-induced cell injury in human umbilical vein endothelial cells: Role of ERK and p38 MAP kinase. J Biol Chem 279:11244-11252. | |
| 20 | Gomelsky, L., J. Sram, O.V. Moskvin, I.M. Horne, H.N. Dodd, J.M. Pemberton, A.G. McEwan, S. Kaplan and M. Gomelsky. 2003. Identification and in vivo characterization of PpaA, a regulator of photosystem formation in Rhodobacter sphaeroides. Microbiol 149:377-388. | |
| 19 | Gomelsky, M. |
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| 18 | Braatsch, S., M. Gomelsky, S. Kuphal, and G. Klug. 2002. A single flavoprotein, AppA, from Rhodobacter sphaeroides integrates both redox and light signals. Mol Microbiol 45:827-836. | |
| 17 |
Gomelsky, M., I.M. Horne, H.-J. Lee, J.M. Pemberton, A.G. McEwan and S. Kaplan. 2000. Domain structure, oligomeric state, and mutation analysis of PpsR, the Rhodobacter sphaeroides repressor of photosystem gene expression. J Bacteriol 182:2253-2261. | |
| 16 | Chistoserdova, L., L. Gomelsky, J.A. Vorholt, M. Gomelsky, Y.D. Tsygankov, and M.E. Lindstrom. 2000. Analysis of two formaldehyde oxidation pathways in Methylobacillus flagellatum KT, a ribulose monophosphate cycle methylotroph. Microbiol 146:233-238. | |
| 1990-99 | 15 | Gomelsky, M., H.-J. Lee and S. Kaplan. 1999. Regulation and mutation analysis of PpsR, the Rhodobacter sphaeroides repressor of photopigment and light harvesting complex II expression, p. 131-138. In The Phototrophic Prokaryotes (G. A. Peschek, W. Loffelhardt and G. Schmetterer, eds.). Kluwer Academic/ Plenum Publishers. New York, Boston, Dordrecht, London, Moscow. |
| 14 | Zeilstra-Ryalls, J.H., M. Gomelsky, J.M. Eraso, A.A. Yeliseev, J.P. O'Gara and S. Kaplan. 1998. Control of photosystem formation in Rhodobacter sphaeroides. Minireview. J Bacteriol 180:2801-2809. | |
| 13 | Gomelsky, M. and S. Kaplan. 1998. AppA, a redox regulator of photosystem formation in Rhodobacter sphaeroides 2.4.1 is a flavoprotein. Identification of a novel FAD binding domain. J Biol Chem 273:35319-35325. | |
| 12 | Zeilstra-Ryalls, J.H., M. Gomelsky, A.A. Yeliseev, J.M. Eraso and S. Kaplan. 1998. Transcriptional regulation of photosynthetic operons in Rhodobacter sphaeroides. Methods Enzymol 297:151-166. | |
| 11 | Serebrijski, I., M. Gomelsky, E. Bashkirova, A. Chistoserdov and Y.D. Tsygankov. 1998. Refined genetic map of the obligate methylotroph Methylobacillus flagellatum. Mol Gen Genet 258:133-138. | |
| 10 | Gomelsky, M. and S. Kaplan. 1997. Molecular genetic evidence suggesting interactions between AppA and PpsR in regulation of photosynthesis gene expression in Rhodobacter sphaeroides 2.4.1. J Bacteriol 179:128-134. | |
| 9 | O'Gara, J. P., M. Gomelsky, and S. Kaplan. 1997. Molecular genetic characterization of multiple loci involved in tellurite resistance in Rhodobacter sphaeroides. Appl Environ Microbiol 63:4713-4720. | |
| 8 | Gomelsky, M., F. Biville, F. Gasser and Y.D. Tsygankov. 1996. Identification of the pqqDGC genes involved in pyrroloquinoline quinone production in an obligate methylotroph, Methylobacillus flagellatum. FEMS Microbiol Lett 141:169-176. | |
| 7 | Gomelsky, M. and S. Kaplan. 1996. The Rhodobacter sphaeroides 2.4.1 rho gene: expression and genetic analysis of structure and function. J Bacteriol 178:1946-1954. | |
| 6 | Gomelsky, M. and S. Kaplan. 1995. appA, a novel gene encoding a trans-acting factor involved in the regulation of photosynthesis gene expression in Rhodobacter sphaeroides 2.4.1. J Bacteriol 177:4609-4618. | |
| 5 | Gomelsky, M. and S. Kaplan. 1995. Isolation of regulatory mutants in photosynthesis gene expression in Rhodobacter sphaeroides 2.4.1 and partial complementation of a PrrB mutant by the HupT histidine-kinase. Microbiol 141:1805-1819. | |
| 4 | Gomelsky, M. and S. Kaplan. 1995. Genetic evidence that PpsR from Rhodobacter sphaeroides 2.4.1 functions as a repressor of puc and bchF expression. J Bacteriol 177:1634-1637. | |
| 3 | Gomelsky, M.V., E.R. Gak, A.Y. Chistoserdov, A.P. Bolotin and Y.D. Tsygankov. 1991. Methylobacillus flagellatum recA gene: specificity of regulation, structure and functions, p. 213-218. In Molecular Basis of Genetic Processes. Nauka. Moscow, USSR (in Russian). | |
| 2 | Gomelsky, M., E. Gak, A. Chistoserdov, A. Bolotin and Y.D. Tsygankov. 1990. Cloning, sequence and expression in Escherichia coli of the Methylobacillus flagellatum recA gene. Gene 94:69-75. | |
| 1 | Tsygankov, Y. D., M. V. Gomelsky, G. N. Marchenko and I. G. Serebrijski. 1990. Genetics of methylotrophic bacteria. In Proc 6th Intl Symp on Genetics of Industrial Microorganisms. 2:645-656. Societe Francaise de Microbiologie. Strasbourg, France. |
Manuscripts Under Review
| • | Russell, M.H., A.N. Bible, X. Fang, J. Gooding, S. Campagna, M. Gomelsky, and G. Alexandre. Integration of the second messenger c-di-GMP into the chemotactic signaling pathway promotes sensory adaptation. (Mbio) |
| • | Chen, L.H., Z.T. Güvener, T. Myers-Morales, J.M. Reed, S.E.F. D’Orazio, K.W. Miller, and M. Gomelsky. Cyclic di-GMP-dependent signaling pathways in the pathogenic firmicute Listeria monocytogenes. (PLoS Pathogens) |
| • | Hu, J., B. Wang, X. Fang, W.J. Means, R.J. McCormick, M. Du, M. Gomelsky, and M.J. Zhu. Role of c-di-GMP signaling in cattle gut colonization and virulence of E. coli O157:H7. (BMC Microbiol) |
