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University of Wyoming

Faculty, Staff and Graduate Assistants

Jun Ren
Personal biography

Jun Ren
Professor, School of Pharmacy
Cell signaling, oxidative stress and apoptosis in neurodegenerative and cardiovascular diseases

Pre-Med: Beijing University
M.D. Peking Union Medical College/Xinjiang Medical University
Ph.D. University of Alberta
Post doctoral: Wayne State University
jren@uwyo.edu • (307) 766-6131

Publications:

REFEREED JOURNAL ARTICLES

2005

Li, S-Yan; Du, M.; Dolence, E.K.; Fang, X.; Mayer, G.; Ceylan-Isik, A.F.; LaCour, K.; Yang, X.; Wilbert, J.C.; Sreejayan, N.; Ren, J. “Aging induces cardiac diastolic dysfunction, oxidative stress, accumulation of advanced glycation end products and protein modification” Aging Cell 2005 4, 57-64.

2004

Davidoff AJ, Mason MM, Davidson MB, Carmody MW, Hintz KK, Wold LE, Podolin DA, Ren J. Sucrose-induced cardiomyocyte dysfunction is both preventable and reversible with clinically relevant treatments. Am. J. Physiol. Endo. Metab. 286: E718-E724, 2004.

Li SY, Gomelski M, Duan J, Zhang Z, Gomelski L, Zhang X, Epstein PN, Ren J. Overexpression of aldehyde dehydrogenase-2 transgene attenuates acetaldehyde-induced apoptosis in human umbilical vein endothelial cells: Role of ERK and p38 MAP kinase. J. Biol. Chem. 279:11244-11252, 2004.

Norby FL, Aberle NS II, Kajstura J, Anversa P, Ren J. Transgenic overexpression of insulin-like growth factor I prevents streptozotocin-induced cardiac contractile dysfunction and ?-adrenergic response in ventricular myocytes. J. Endocrinol. 180: 175-182, 2004.

Ren J, Porter JE, Wold LE, Aberle NS II, Muralikrishnan D, Haselton JR. Depressed contractile function and adrenergic responsiveness of cardiac myocytes in an experimental model of Parkinson disease, the MPTP-treated mouse. Neurobiol Aging. 25: 131-138, 2004.

Ren J, Zhang X, Scott GI, Esberg LB, Ren BH, Culver B, Chen AF. Adenovirus gene transfer of recombinant eNOS enhances contractile function in ventricular myocyte. J. Cardiovasc. Pharm. 43: 171-177, 2004.

2003

Privratsky JR, Wold LE, Sowers JR, Quinn MT, Ren J. AT1 blockade prevents glucose toxicity-induced cardiac dysfunction in ventricular myocytes: Role of the AT1 receptor and NADPH oxidase. Hypertension 42: 206-212, 2003.

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Press releases: