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University of Wyoming

Faculty, Staff and Graduate Assistants

Donal C. Skinner
Personal biography

Donal C. Skinner
Associate Professor, Department of Zoology and Physiology
Neuroendocrinology
Reproduction
Comparative Endocrinology
Neuroscience


B.S. Rhodes University, South Africa
B.S. University of the Witwatersrand, South Africa
Ph.D. University of Cambridge, UK
Post-Doctoral: Institut National de
la Recherche Agronomique (France), University of Cambridge, UK
dcs@uwyo.edu • 307-766-3321

Research:


Publications:

REFEREED JOURNAL ARTICLES

In Press

Albertson A, Navratil A, Cherrington B, Duittoz, A, Mignot M & Skinner DC GnRH receptor expression in the ovine and murine hypophysis. Endocrinology

Constantin S, Ottogalli M, Tanguy D, Sizaret P-Y, Skinner DC, Wray S & Duittoz AH GnRH-1 regulates embryonic GnRH-1 neurones. J Neuroendocrinol

Skinner DC & Caraty A 2002 The measurement and possible function of GnRH in cerebrospinal fluid in ewes. Reproduction Suppl 59. In Press

2007

Bliss SP, Navratil A, Breed M, Skinner DC, Clay CM & Roberson MS 2007 Signaling complexes associated with the type I GnRH receptor: Colocalization of ERK2 and GnRH receptor within lipid rafts. Mol Endocrinol 28: 531-549

Lutz L, Schofield N*, Crowe C*, Dufourny L & Skinner DC 2007 No effect of nutrient restriction from gestational days 28 to 78 on immunocytochemically detectable growth hormone-releasing hormone (GHRH) neurons and GHRH receptor colocalization in somatotropes of the ovine female fetus. J Chem Neuroanat 33: 34-41

2006

Lutz L, Dufourny L & Skinner DC 2006 Effect of nutrient restriction on the somatotropes and substance P-immunoreactive cells in the pituitary of the female ovine fetus. Growth Horm IGF Res. 16:108-18

2005

Dufourny L & Skinner DC 2005 Immunocytochemical colocalization of galanin receptor 1 (GAL-R1) in GnRH neurons in the ovine hypothalamus: Effect of sex, season and oestrous cycle Brain Res 1054: 73-81

Dufourny L, Caraty A, Clarke IJ, Robinson JE & Skinner DC 2005 Progesterone-receptive β-endorphin and dynorphin B neurons in the arcuate nucleus project to regions of high density GnRH neurons in the ovine preoptic area. Neuroendocrinology 81: 139-149

Dufourny L, Caraty A, Clarke IJ, Robinson JE & Skinner DC 2005 Progesterone-receptive dopaminergic and NPY neurons in the arcuate nucleus project to regions of high density GnRH neurons in the ovine preoptic area. Neuroendocrinology 82:21-31

Mignot M & Skinner DC 2005 Colocalization of GH, TSH and prolactin, but not ACTH, with βLH-immunoreactivity: evidence for pluripotential cells in the ovine pituitary. Cell Tiss Res 319: 413 - 421

Skinner DC & Dufourny L 2005 Estrogen receptor β expression in the ovine hypothalamus: Distribution and colocalization with GnRH J Neuroendocrinol 17: 29-39

2003

Dufourny L & Skinner DC 2003 Colocalization of progesterone receptors and thyroid hormone receptors α in the ovine diencephalon: no effect of estradiol. Neuroendocrinology 77: 51-58

Dufourny L, Schofield N* & Skinner DC 2003 Galanin expression in ovine GnRH neurons: no effects of gender or reproductive status. J Neuroendocrinol 15: 1062-1069

Scanlan N, Dufourny L & Skinner DC 2003 Somatostatin-14 neurons in the ovine hypothalamus: colocalization with estrogen receptor α and somatostatin-28(1-12) immunoreactivity, and activation in response to estradiol. Biol Reprod 69: 1318-1324

Skinner DC & Caraty A 2003 Prolactin release during the estradiol-induced LH surge in ewes: modulation by progesterone but no evidence for prolactin-releasing peptide involvement. J Endocrinol 177: 453-460

Skinner DC, Head S* & Oliver J* 2003 Growth hormone-releasing hormone neurones in the cat do not express progesterone receptors. Cell Tissue Res. 311: 267-270

Skinner JD, Moss DG* & Skinner DC 2003 Inherent seasonality in the breeding seasons of African mammals: evidence from captive breeding. Trans Roy Soc Sth Afr 57: 25-34

Vonnahme KA, Hess BW, Hansen TR, McCormick R, Rule DC, Moss GE, Murdoch WJ, Nijland M, Nathanielsz PW, Skinner DC & Ford SP 2003 A constant 50% nutrient restriction from day 28 to 78 of gestation in ewes markedly reduces fetal growth rate in association with bilateral ventricular hypertrophy. Biol Reprod 69: 133-140

2002

Dufourny L & Skinner DC 2002 Influence of estradiol on NADPH diaphorase/neuronal nitric oxide synthase activity and colocalization with progesterone- or type II glucocorticoid-receptors in the ovine hypothalamus. Biol Reprod. 67: 829-836

Dufourny L & Skinner DC 2002 Progesterone receptor, estrogen receptor α and the type II glucocorticoid receptor are coexpressed in the same neurons of the ovine preoptic area and arcuate nucleus: a triple immunolabeling study. Biol Reprod. 67: 1605-1612

Dufourny L & Skinner DC 2002 Type II glucocorticoid receptors in the ovine hypothalamus: distribution, influence of estrogen and absence of colocalisation with GnRH. Brain Res. 946: 79-86

Evans NP, Richter TA, Skinner DC, Robinson JE 2002 On the neuroendocrine mechanisms of GnRH surge induction by estradiol. Reproduction Suppl 59: 57-66

Foradori CD, Coolen LM, Fitzgerald, ME, Skinner DC, Goodman RL & Lehman, MN 2002 Coexpression of progesterone receptors in parvicellular dynorphin neurons of the ovine preoptic are and hypothalamus. Endocrinology. 143: 4366-4374

Goodman RL, Gibson M, Skinner DC & Lehman MN 2002 Neuroendocrine control of pulsatile GnRH secretion during the ovarian cycle: Evidence from the ewe. Reproduction Suppl 59: 41-56

Malpaux B, Tricoire H, Daveau A, Locatelli A, Chemineau P & Skinner DC 2002 Melatonin and seasonal reproduction: understanding the neuroendocrine mechanisms using the sheep as a model. Reproduction Suppl 59: 167-179

Scanlan N & Skinner DC 2002 Estradiol modulation of growth hormone secretion in the ewe: no growth hormone-releasing hormone neurons and few somatotropes express estradiol receptors. Biol Reprod. 66: 1267-1273

Scanlan N & Skinner DC 2002 Estradiol modulation of growth hormone secretion in the ewe: no growth hormone-releasing hormone neurons and few somatotropes express estradiol receptors. Biology of Reproduction 66: 1267-1273

Skinner DC & Caraty A 2002 The measurement and possible function of GnRH in cerebrospinal fluid in ewes. Reproduction Suppl 59: 25-39

Skinner DC, Cilliers SD* & Skinner JD 2002 The effect of ram introduction on the oestrous cycle of springbok ewes (Antidorcas marsupialis). Reproduction. 124: 509-513

2001

Richter TA, Spackman DS*, Robinson JE, Dye S, Harris TG, Skinner DC & Evans NP 2001 Role of endogenous opioid peptides in mediating progesterone-induced disruption of the activation and transmission stages of the GnRH surge induction process. Endocrinology 142: 5212-5219

Skinner DC, Caraty A & Allingham R 2001 Unmasking the progesterone receptor in the preoptic area and hypothalamus of the ewe: no colocalization with GnRH neurons. Endocrinology. 142: 573-579

Skinner DC, Caraty A & Allingham R 2001 Unmasking the progesterone receptor in the preoptic area and hypothalamus of the ewe: no colocalization with GnRH neurons. Endocrinology 142: 573-579

Skinner DC, Richter TA, Malpaux B & Skinner JD 2001 Annual ovarian cycles in an aseasonal breeder, the springbok (Antidorcas marsupialis) Biol Reprod. 64: 1176-1182

Skinner DC, Richter TA, Malpaux B & Skinner JD 2001 Annual ovarian cycles in an aseasonal breeder, the springbok (Antidorcas marsupialis) Biology of Reproduction 64: 1176-1182

Skinner JD & Skinner DC 2001 Significance of aseasonal breeding in arid adapted antelope in southern Africa. Ecology of Desert Environments pages 391-403

2000

Chabbert-Buffet N, Skinner DC, Caraty A & Bouchard P 2000 Neuroendocrine actions of progesterone. Steroids 65: 613-620

Robinson JR, Healey AE, Harris TG, Messent AE, Skinner DC, Taylor JA & Evans NP 2000 The negative feedback action of progesterone on luteinizing hormone release is not associated with changes in GnRH mRNA expression in the ewe J Neuroendocrinol 12: 121-130

Skinner DC, Harris TG & Evans NP 2000 Duration and amplitude of the luteal phase progesterone increment times the estradiol-induced LH surge in ewes. Biol Reprod 63: 1135-1142

Skinner DC, Harris TG & Evans NP 2000 The duration and amplitude of the luteal phase progesterone increment times the estradiol-induced LH surge in ewes. Biology of Reproduction 63: 1135-1142

1999

Skinner DC & Malpaux B 1999 High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Galen vein blood recirculating through the choroid plexus. Endocrinology 140: 4399-4405

1998

Skinner DC, Evans NP, Bouchard P, Delaleu B & Caraty A 1998 The negative feedback actions of progesterone on gonadotropin-releasing hormone secretion are transduced by the classical progesterone receptor. Proceedings of the National Academy of Science 95: 10978-10983

1997

Skinner DC & Herbison AE 1997 Effects of photoperiod on estrogen receptor, tyrosine hydroxylase, neuropeptide Y and ß-endorphin immunoreactivity in the ewe hypothalamus. Endocrinology 138:2585-2595

Skinner DC, Caraty A, Malpaux B & Evans NP 1997 Simultaneous measurement of GnRH in the third ventricular cerebrospinal fluid and hypophyseal portal blood of the ewe. Endocrinology 138: 4699-4704

1995

Skinner DC & Robinson JE 1995 Melatonin-binding sites in the gonadotroph- enriched zona tuberalis of ewes. Journal of Reproduction and Fertility 104:243-250

Press releases: