University of Wyoming

Dong, F. and J. Ren. Adiponectin improves cardiomyocyte contractile function in db/db diabetic obese mice. Obesity (Silver Spring) 17(2): 262-8. 2009.

Doser, T. A., S. Turdi, et al. Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction.Circulation 119(14): 1941-9. 2009

Guo, R., H. Ma, et al. Metallothionein alleviates oxidative stress-induced endoplasmic reticulum stress and myocardial dysfunction.J Mol Cell Cardiol. 2009.[Epub ahead of print]

Guo, R., L. Zhong, et al. (2009). Overexpression of aldehyde dehydrogenase-2 (ALDH2) attenuates chronic alcohol exposure-induced apoptosis, change in Akt and Pim signaling in liver.Clin Exp Pharmacol Physiol. 2009. [Epub ahead of print]

Li, S. Y., S. A. Gilbert, et al. Aldehyde dehydrogenase-2 (ALDH2) ameliorates chronic alcohol ingestion-induced myocardial insulin resistance and endoplasmic reticulum stress. J Mol Cell Cardiol. 2009. [Epub ahead of print]

Ren, J., A. J. Davidoff, et al. Creatine kinase inhibitor iodoacetamide antagonizes calcium-stimulated inotropy in cardiomyocytes.Clin Exp Pharmacol Physiol.  36(2):141-5, 2009.

Zhao, P., J. Wang, et al. A newly synthetic chromium complex-chromium (D-phenylalanine)3 activates AMP-activated protein kinase and stimulates glucose transport. Biochem Pharmacol. 77(6): 1002-10, 2009.  

Book Chapters and Reviews       
Ge, W. and J. Ren. Combined L-/T-type calcium channel blockers: ready for prime time. Hypertension 53(4): 592-4. 2009. 
 
Zhao, P., A. C. Sharma, et al. Pathogenesis and therapy of autoimmunity-induced dilated cardiomyopathy. Front Biosci. 14: 1708-15, 2009.  

Ren, J. and R. O. Kelley. Cardiac Health in Women With Metabolic Syndrome: Clinical Aspects and Pathophysiology.Obesity (Silver Spring). 2009.[Epub ahead of  print]

2008

Dong F, Ford SP, Nijland MJ, Nathanielsz PW, Ren J. Influence of maternal undernutrition and overfeeding on cardiac ciliary neurotrophic factor receptor and  ventricular size in fetal sheep. J. Nutri. Biochem. 19:409-414, 2008.

Dong F, Kandadi MR, Ren J, Sreejayan N. Chromium (D-phenylalanine)3 supplementation improves glucose disposal, insulin signaling and Glut-4 membrane translocation in a dietary mouse model of insulin resistance, J. Nutr. 138:1846-1851, 2008.

Duan J, Xu HS, Dai S, Wang X, Wu Y, Zhang Y, Sun R, Ren J. Phytoestrogen α-zearalanol inhibits homocysteine-induced endothelin-1 expression and oxidative stress in human umbilical vein endothelial cells. Atherosclerosis 197: 549-555, 2008.

Fang CX, Dong F, Thomas DP, Ma H, He L, Ren J. Hypertrophic cardiomyopathy in high fat diet-induced obesity: Role of suppression of Forkhead transcription factor and atrophy gene transcription. Am. J. Physiol. Heart Circ. Physiol. 295: H1206-H1215, 2008.

Gao R, Zhu BH, Tang SB, Wang JF, Ren J. Scutellarein inhibits hypoxia- and moderately-high glucose-induced proliferation and VEGF expression in human retinal endothelial cells. Acta Pharmacol. Sin. 29: 707-712, 2008.

Li J, Zhang HF, Wu F, Nan Y, Ma J, Guo WY, Wang HC, Ren J, Das UN, Gao F. Insulin inhibits TNF-α induction in myocardial ischemia/reperfusion: Role of Akt and eNOS phosphorylation. Crit. Care Med. 36:1551-1558, 2008.

Li LL, Ma XL, Ran XJ, Sun XF, Xu LM, Ren J, Mao XM. Genetic polymorphism of peroxisome proliferator-activated receptor-[gamma]2 pro12Ala on ethnic susceptibility to diabetes in Uygurs, Kazaks and Hans subjects. Clin. Exp. Pharm. Physiol 35: 187–191, 2008.

Li LL, Liu XY, Ran JX, Wang Y, Luo X, Wang T, Ren J, Aisha M, Abudureheman R, Xiawudong A, Zhang XC, Mao XM. Analysis of prevalence and risk factors of hypertension among Uygur adults in Tushala and Hetian of Xinjiang Uygur autonomous region. Cardiovasc. Toxicol. 8:87-91, 2008.

Li Q, Ceylan-Isik AF, Li J, Ren J. Deficiency of insulin-like growth factor 1 (IGF-1) reduces sensitivity to aging-associated cardiomyocyte dysfunction.Rejuvenation Res. 11: 725-733, 2008.

Li SY, Ren J. Cardiac overexpression of alcohol dehydrogenase exacerbates chronic ethanol ingestion-induced myocardial dysfunction and hypertrophy: Role of insulin signaling and ER stress. J. Mol. Cell. Cardiol. 44: 992-1001, 2008.

Ma L, Zhu BH, Chen XP, Liu J, Guan YY, Ren J. Abnormalities of sarcoplasmic reticulum Ca2+ mobilization in aortic smooth muscle cells from streptozotocin-induced diabetic rats. Clin. Exp. Pharm. Physiol 35:568-573, 2008.

Ren J, Privratsky JR, Yang X, Dong F, Carlson EC. Metallothionein alleviates glutathione depletion-induced oxidative cardiomyopathy in murine hearts. Crit.Care Med. 36:2106-2116, 2008.

Ren J, Duan J, Thomas DP, Yang X, Sreejayan N, Sowers JR, Leri A, Kajstura J, Gao F, Anversa P. IGF-1 alleviates diabetes-induced RhoA activation, eNOS uncoupling and myocardial contractile dysfunction. Am. J. Physiol. Regul. Integr. Comp. Physiol. 294: R793-802, 2008.

Ren J, Zhu BH, Relling DP, Esberg LB, Ceylan-Isik AF. High fat diet-induced obesity leads to resistance to leptin-induced cardiomyocyte contractile response. Obesity 16:2417-2423, 2008.

Sreejayan N, Dong F, Kandadi MR, Yang X, Ren J. Chromium improves glucose intolerance, insulin resistance and hepatic ER stress in obese mice. Obesity 16:1331-1337, 2008.

Sreejayan N, Yang X, Palanichamy K, Dolence D, Ren J. Antioxidant properties of argpyrimidine. Eur. J. Pharmacol, 593: 30–35, 2008.

Liu Y, Dolence J, Ren J, Rao MNA, Sreejayan N. Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function. J. Cardiovasc. Pharmacol. 52: 422-429, 2008.

Sun JB, Duan JH, Dai SL, Ren J, Guo L, Jiang W, Li Y. Preparation and anti-tumor efficiency evaluation of doxorubicin-loaded bacterial magnetosomes, the  magnetic nanoparticles as drug carriers isolated from Magnetospirillum Gryphiswaldense. Biotechnol. Bioengineering 101: 1313-1320, 2008.

Tao YC, Ma XM, Xie Z, Ran X, Wang Y, Luo X, Hu M, Gen W, Zhang M, Wang T, Ren J, Li LL. The prevalence of type 2 diabetes and hypertension in Uygur and Kazak populations. Cardiovasc. Toxicol. 8:155-159, 2008.

Turdi S, Xu PS, Li Q, Shen Y, Kerram P, Ren J. Amidization of doxorubicin alleviates doxorubicin-induced contractile dysfunction and reduced survival in murine cardiomyocytes. Toxicol. Lett. 178: 197-201, 2008

Xu H, Duan J, Wang W, Dai S, Wu Y, Sun R, Ren J. Reactive oxygen species mediate oxidized LDL-induced endothelin-1 gene expression via extracellular signal-regulated kinase (ERK) pathway in vascular endothelial cells. J. Hypertens. 26: 956-963, 2008.

Xu H, Duan J, Dai S, Wu Y, Sun R, Ren J. α­Zearalanol attenuates oxLDL-induced ET-1 gene expression, ET-1 secretion and redox-sensitive intracellula signaling activation in human umbilical vein endothelial cells. Toxicol. Lett. 179:163-168, 2008.

Xu PS, Li SY, Li Q, Van Kirk EA, Ren J, Zhang Z, Radosz M, Murdoch WJ, Shen Y. Virion-mimicking nanocapsules from pH-controlled hierarchical self-assembly for gene delivery. Angew Chem. Int. Edit. 47: 1260-1264, 2008.

Zhao P, Xiao XY, Kim AS, Leite MF, Xu JX, Zhu XL, Ren J, Li J. c-Jun inhibits thapsigargin-induced ER stress through up-regulation of DSCR1/Adapt78. Exp Biol. Med. 233:1289-1300, 2008.

Zhao P, Su G, Xiao XY, Hao E, Zhu XL, Ren J. Chinese medicinal herb Radix Astragali suppresses cardiac contractile dysfunction and inflammation in a rat model of autoimmune myocarditis. Toxicol. Lett. 182: 29-35, 2008.

Book Chapters and Reviews

Ceylan-Isik AF, Fliethman RM, Wold LE, Ren J. Herbal and traditional Chinese medicine for treatment of cardiovascular complications in diabetes mellitus. Curr. Diabetes Rev. 4:320-328, 2008.

Ren J. Wide spectrum of presentation and variable mechanisms of compromised cardiac function in multiple organ dysfunction syndrome. J. Organ Dysfunction 4: 239 – 248, 2008.

Ren J, Wold LE. Mechanisms of alcoholic heart disease. Therapeutic Advances in Cardiovascular Disease  2:497-506, 2008.
Ren J, Ma H. Impaired cardiac function in leptin deficient mice. Curr. Hypertension Report. 10: 448-453, 2008.
 
Ren J. Wang YJ. One world, one mission – 2007 American Heart Scientific Session. New Drug Invest. Tribune 44: 7-8, 2008.

Ren J. Leptin and cardiac dysfunction in obesity. Chin Med Tribune 34:C5, 2008.


2007

Dong F*, Yang X*, Sreejayan N, Ren J. Chromium (D-phenylalanine)3 improves obesity-induced cardiac contractile defect in ob/ob mice. Obesity 15: 2699-2710, 2007. (*equal first authorship)
 
Dong F, Ren J. Fidarestat improves cardiomyocyte contractile function in db/db diabetic obese mice through a histone deacetylase Sir2-dependent mechanism. J. Hypertens. 25: 2138-2147, 2007.

Dong F, Li Q, Sreejayan N, Nunn JM, Ren J. Metallothionein prevents high fat diet-induced cardiac contractile dysfunction: Role of peroxisome proliferator-activated receptor γ coactivator-1α and mitochondrial biogenesis. Diabetes 56:2201-2012, 2007.
 
Fang CX, Yang X, Sreejayan N, Ren J. Acetaldehyde promotes rapamycin-dependent activation of p70S6K and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells. Exp. Neurol. 203:196-204, 2007.

Li LL, Kang XL, Ran XJ, Wang CH, Huang L, Wang Y, Ren J, Luo X, Mao XM. Association of 45T/G polymorphism in adiponectin gene and plasma adiponectin level with type 2 diabetes. Clin. Exp. Pharm. Physiol 34:1287-1290, 2007.
 
Li Q, Wu S, Li SY, Lopez FL, Du M, Kajstura J, Anversa P, Ren J. Cardiac specific overexpression of insulin-like growth factor-1 (IGF-1) attenuates aging-associated cardiac diastolic contractile dysfunction and protein  damage. Am J Physiol: Heart Circ Physiol 292: H1398-H1403, 2007.

Li Q, Ren J. Chronic alcohol consumption reduces activation of mammalian target of rapamycin (mTOR) and ribosomal p70S6 kinase in cerebral cortex. Exp. Neurol.Neurol. 204: 840-844, 2007.

Li Q, Ren J. Influence of cardiac specific overexpression of insulin-like growth factor-1 on life span and aging-associated changes in cardiac intracellular Ca2+. Aging Cell 6: 799-806, 2007.

Li Q, Yang X, Sreejayan N, Ren J. Insulin-like growth factor I deficiency prolongs survival and antagonizes paraquat–induced cardiomyocyte dysfunction: Role of oxidative stress. Rejuvenation Res. 10:501-512, 2007.

Li SY, Sigmon VK, Babcock SA, Ren J. Advanced glycation endproducts induce ROS accumulation, apoptosis, MAP kinase activation and nuclear O-glcNAcylation in human cardiac myocytes. Life Sci 80:1051-1056, 2007.

Relling DP, Esberg LB, Johnson WT, Murphy EJ, Carlson EC, Saari JT, Lukaski HC, Ren J. Dietary interaction of high fat and marginal copper deficiency on cardiac contractile function. Obesity 15: 1242 – 1257, 2007.

Ren J, Li Q, Wu S, Li SY, Babcock SA. Cardiac overexpression of antioxidant catalase attenuates aging-induced cardiomyocyte relaxation dysfunction. Mech. Aging Dev. 128: 276-285, 2007.

Ren J. Influence of gender on oxidative stress, lipid peroxidation, protein damage and apoptosis in hearts and brains from spontaneously hypertensive rats. Clin. Exp. Pharm. Physiol. 34: 432-438, 2007.

Ren J. Interaction between high fat diet and alcohol dehydrogenase on ethanol-elicited cardiac depression in murine myocytes. Obesity 15: 2932-2941, 2007.

Saari JT, Wold LE, Duan J, Ren J, Carlson HL, Bode AM, Lentsch AB, Zeng H, Schuschke DA. Cardiac nitric oxide synthases are elevated in dietary copper deficiency. J. Nutr. Biochem. 18: 443-448, 2007.

Shen QW, Zhu MJ, Tong J, Ren J, Du M. Ca2+/calmodulin-dependent protein kinase kinase is involved in AMP-activated protein kinase activation by {alpha}-lipoic acid in C2C12 myotubes. Am. J. Physiol. Cell Physiol. 293: C1395 - C1403, 2007.

Stratton MS, Yang X, Sreejayan N, Ren J. Impact of insulin-like growth factor I on migration, proliferation and Akt-ERK signaling in early and late-passages of vascular smooth muscle cells. Cardiovasc. Toxicol. 7:273-281, 2007.

Sun JB, Duan JH, Dai SL, Ren J, Zhang YD, Tian JS, Li Y. In Vitro and in vivo antitumor effects of doxorubicin loaded with bacterial magnetosomes on H22 Cells: the magnetic bio-nanoparticles as drug carriers. Cancer Lett. 258:109-117, 2007.

Turdi S, Li Q, Lopez FL, Ren J. Catalase alleviates cardiomyocyte dysfunction in diabetes: Role of Akt, forkhead transcriptional factor and silence information regulator 2. Life Sci 81: 895-905, 2007.

Wu S, Li Q, Du M, Li SY, Ren J. Cardiac overexpression of catalase prolongs lifespan, attenuates aging-induced cardiomyocyte contractile dysfunction and protein damage. Clin. Exp. Pharm. Physiol. 34: 81-87, 2007.

Zhang QJ, Li QX, Zhang HF, Zhang KR, Guo WY, Wang HC, Fan M, Zhou Z, Cheng HP, Ren J, Gao F. Aerobic exercise sensitizes myocardial contractile response to insulin - Role of Akt-dependent eNOS activation. Cardiovasc Res. 75: 369-380, 2007.

Zhang X, Dong F, Mayer GE, Bruch DC, Ren J, Culver B. Selective inhibition of cyclooxygenase-2 exacerbates methamphetamine-induced dopamine depletion in the striatum in rats. Neuroscience 150: 950-958, 2007.

Book Chapters and Reviews

Dong F, Ren J. Fitness or fatness - the debate continues for the role of leptin in obesity-associated heart dysfunction. Curr Diabetes Rev. 3: 159-164, 2007.

Ghosh S, Rodrigues B, Ren J. Rat models of cardiac insulin resistance. In “Vascular Biology Protocols” a part of the “Methods in Molecular Medicine” Book Series. Ed: Sreejayan N and Ren J, 1st ed. The Humana Press Inc., Totowa, New Jersey, USA, Methods Mol Med. 139: 113-143, 2007.

Jay MA, Ren J. Peroxisome proliferator-activated receptor (PPAR) in metabolic syndrome. Curr Diabetes Rev. 3: 33-39, 2007.

Li SY, Ren J. Assessment of protein glycoxidation in ventricular tissues. In “Vascular Biology Protocols” a part of the “Methods in Molecular Medicine” Book Series. Ed: Sreejayan N and Ren J, 1st ed. The Humana Press Inc., Totowa, New Jersey, USA, Methods Mol Med. 139: 313-328, 2007.

Ren J. Acetaldehyde and alcoholic cardiomyopathy: lessons from the ADH and ALDH-2 transgenic models. Novartis. Found. Symp. 285: 69-79, 2007.
Ren J, Xu JX. Issue of cardiovascular safety of rosiglitazone: a revisit of its clinical application. New Drug Invest. Tribune 39:24, 2007.
 
Ren J. New technology, new concept - American College of Cardiology 2007. New Drug Invest. Tribune 35: 21, 2007. 

Wold LE, Ren J. Mechanical measurement of contractile function of the isolated ventricular myocytes.  In “Vascular Biology Protocols” a part of the “Methods in Molecular Medicine” Book Series. Ed: Sreejayan N and Ren J, 1st ed. The Humana Press Inc., Totowa, New Jersey, USA, Methods Mol Med. 139:263-270, 2007.

2006

Ceylan-Isik AF, Wu S, Li Q, Li SY, Ren J. High-dose benfotiamine rescues cardiomyocyte contractile dysfunction in streptozotocin-induced diabetes mellitus. J. Appl Physiol. 100:150-156, 2006.

Ceylan-Isik AF, LaCour KH, Ren J. Sex difference in cardiomyocyte function in normal and metallothionein transgenic mice: the effect of diabetes mellitus. J. Appl. Physiol. 100: 1638-1646, 2006.

Dong F, Zhang X, Yang X, Yang H, Zhang Z, Culver B, Ren J. Impaired cardiac contractile function in ventricular myocytes from leptin deficient ob/ob obese mice. J. Endocrinol 188: 25-36, 2006.

Dong F, Zhang X, Ren J. Leptin regulates cardiomyocyte contractile function through endothelin-1 receptor - NADPH Oxidase pathway. Hypertension 47: 222-229, 2006.
 

Dong F, Fang CX, Yang XP, Zhang X, Ren J. Cardiac over-expression of catalase rescues insulin resistance-induced cardiac contractile dysfunction: Role of oxidative stress, protein carbonyl formation and insulin sensitivity. Diabetologia 49:1421-1433, 2006.

Dong F, Taylor MM, Samson WK, Ren J. Intermedin (Adrenomedullin-2) enhances cardiac contractile function via a protein kinase C and protein kinase A-dependent pathway in murine ventricular myocytes. J. Appl. Physiol. 101: 778-784, 2006.

Duan J, Dai S, Fang CX, Sun RY, Shavali S, Sharma SK, Ebadi M, Ren J. Phytoestrogen α-zearalanol antagonizes homocysteine-induced imbalance of nitric oxide/endothelin-1 and apoptosis in human umbilical vein endothelial cells (HUVEC). Cell. Biochem. Biophys. 45: 137-145, 2006.

Fang CX, Doser TA, Yang X, Sreejayan N, Ren J. Metallothionein antagonizes aging-induced cardiac contractile dysfunction: Role of PTP1B, insulin receptor tyrosine phosphorylation and Akt. Aging Cell 5: 177-185, 2006.


 

Guo KK, Ren J. Cardiac overexpression of alcohol dehydrogenase (ADH) alleviates aging-associated cardiomyocyte contractile dysfunction: Role of intracellular Ca2+ cycling proteins. Aging Cell 5: 259-265, 2006.

Kim J, Li Q, Fang CX, Ren J. Paradoxical effects of ginkgolide B on cardiomyocyte contractile function under normal and high glucose environments.  Acta Pharmacologica Sinica 27:536-542, 2006.

Li Q, Fang CX, Nunn JM, Zhang J, LaCour KH, Ren J. Characterization of cardiomyocyte excitation-contraction coupling in the FVB/N-C57BL/6 intercrossed “chocolate” brown mice. Life Sci. 80:187-192, 2006.

Li Q, Ren J. Cardiac overexpression of metallothionein attenuates chronic alcohol intake-induced cardiomyocyte contractile dysfunction. Cardiovasc. Toxicol. 6: 173-182, 2006.

Li Q, Ren J. Cardiac overexpression of metallothionein rescues chronic alcohol intake-induced cardiomyocyte dysfunction: Role of Akt, mammalian target of rapamycin and ribosomal p70s6 kinase. Alcohol Alcoholism 41: 585-592, 2006.

Li SY, Yang X, Ceylan-Isik AF, Du M, Sreejayan N, Ren J. Cardiac contractile dysfunction in ob/ob obesity is accompanied with NADPH Oxidase Activation, oxidative modification of sarco(endo)plasmic reticulum Ca2+-ATPase and myosin heavy chain isozyme switch. Diabetologia 49:1434-1346, 2006.

Li SY, Li Q, Shen J, Dong F, Sigmon VK, Liu Y, Ren J. Attenuation of acetaldehyde-induced cell injury by overexpression of aldehyde dehydrogenase-2 transgene in human cardiac myocytes: Role of MAP kinase signaling. J. Mol. Cell. Cardiol. 40: 283-294, 2006.

Relling DP, Esberg LB, Fang CX, Johnson WT, Murphy EJ, Carlson EC, Saari JT, Ren J. High fat diet induced-juvenile obesity leads to cardiomyocyte dysfunction and upregulation of Foxo3a transcription factor independent of lipotoxicity and apoptosis. J. Hypertension 24:549-561, 2006.

Wold LE, Ceylan-Isik AF, Fang CX, Yang X, Li SY, Sreejayan N, Privratsky JR, Ren J. Metallothionein alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of Ca2+ cycling proteins, NADPH oxidase, poly(ADP-Ribose) polymerase and myosin heavy chain isozyme. Free Rad Biol Med. 40:1419-1429, 2006.

Wu S, Ren J. Benfotiamine alleviates diabetes-induced cerebral oxidative damage independent of advanced glycation end-product, tissue factor and TNF-α. Neurosci Lett 394:158-162, 2006.

Wu S, Fang CX, Kim J, Ren J. Enhanced pulmonary inflammation following experimental intracerebral hemorrhage. Exp. Neurol. 200: 245-249, 2006.

Xu P, Van Kirk EA, Li SY, Murdoch WJ, Ren J, Hussain MD, Radosz M, Shen Y. Highly stable core-surface-crosslinked nanoparticles as cisplatin carriers for cancer chemotherapy. Colloids and Surfaces B: Biointerfaces, 48:50-57, 2006.

Xu P, Li SY, Li Q, Ren J, Van Kirk EA, Murdoch WJ, Radosz M, Shen Y. Biodegradable cationic polyester as an efficient carrier for gene delivery to neonatal cardiomyocytes. Biotechnology and Bioengineering 95:893-903, 2006.

Yang X, Thomas DP, Zhang X, Culver BW, Alexander BM, Murdoch WJ, Rao MNA, Tulis DA, Ren J, Sreejayan N. Curcumin inhibits PDGF-stimulated vascular smooth muscle cell function and injury-induced neointima formation. Arter. Thromb. Vasc. Biol. 26: 85-90, 2006.

Yang X, Li SY, Dong F, Ren J, Sreejayan N. Insulin-sensitizing and cholesterol lowering effects of chromium (phenylalanine)3. J. Inorganic Biochem. 100:1187-1193, 2006.

Yang X, Doser TA, Fang CX, Nunn JM, Janardhanan R, Zhu MJ, Sreejayan N, Quinn MT, Ren J. Metallothionein prolongs survival and antagonizes senescence-associated cardiomyocyte diastolic dysfunction: Role of oxidative stress. FASEB J. 20:1024-1026 (E260-E270), 2006.

Book Chapters and Reviews

Doser TA, Culver B, Ren J. COX-2 inhibitors and cardiovascular event: deja vu du jour. Vascular Disease Prevention 3: 217-221, 2006.

Ebadi M, Brown-Borg H, Ren J, Sharma S, Shavali S, El ReFaey H, Carlson EC. Therapeutic efficacy of selegiline in neurodegenerative disorders and neurological diseases. Curr Drug Targets 7:1513-1529, 2006.

Dong F, Esberg LB, Roughead ZK, Ren J, Saari JT. Increased contractility of cardiomyocytes from copper-deficient rats is associated with up-regulation of the cardiac insulin-like growth factor-I receptor. Am J Physiol: Heart Circ Physiol 289:H78-H84, 2005.

Dong F, Ford SP, Fang  CX, Nijland MJ, Nathanielsz PW, Ren J. Maternal nutrient restriction during early to mid gestation up-regulates cardiac insulin-like growth factor (IGF) receptors associated with enlarged ventricular size in fetal sheep. Growth Horm IGF Res 15: 291-299, 2005.

Dong F, Zhang X, Li SY, Zhang Z, Ren Q, Culver B, Ren J. Possible involvement of NADPH oxidase and JNK in homocysteine-induced oxidative stress and apoptosis in human umbilical vein endothelial cells. Cardiovasc. Toxicol. 5: 9-20, 2005.

Dong F, Zhang X, Wold LE, Ren Q, Zhang Z, Ren J. Endothelin-1 enhances oxidative stress, cell proliferation and reduces apoptosis in human umbilical vein endothelial cells: Role of ETB receptor, NADPH oxidase and caveolin-1. Br. J. Pharmacol. 145: 323-333, 2005.

Dong F, Zhang X, Culver B, Chew, HG, Jr., Kelley RO, Ren J. Dietary iron deficiency induces ventricular dilation, mitochondrial ultra-structural aberrations and cytochrome C release: Involvement of nitric oxide synthase and protein tyrosine nitration. Clin Science 109: 277-286, 2005.

Fang CX, Dong F, Ren BH, Epstein PN, Ren J. Metallothionein alleviates insulin resistance-induced cardiac contractile dysfunction: Role of Akt phosphorylation, PTB1B, PPARγ and c-Jun. Diabetologia 48:2412-2421, 2005.

Gupta A, Aberle II NS, Ren J, Sharma AC. Endothelin-converting enzyme-1-mediated signaling in adult rat ventricular myocyte contractility and apoptosis during sepsis. J. Mol. Cell. Cardiol. 38: 527-537, 2005.

Gupta A, Aberle II NS, Kapoor R, Ren J, Sharma A. Bigendothelin-1 via p38-MAPK dependent mechanism regulates adult rat ventricular myocyte contractility in sepsis. Biochimica et Biophysica Acta 1741:127-139, 2005.

Li SY, Du M, Dolence EK, Fang CX, Mayer GE, Ceylan-Isik AF, LaCour KH, Yang X, Wilbert CJ, Sreejayan N, Ren J. Aging induces cardiac diastolic dysfunction, oxidative stress, accumulation of advanced glycation endproducts and protein modification. Aging Cell 4: 57-64, 2005.

Li SY, Golden KL, Jiang Y, Wang GJ, Privratsky JR, Zhang X, Eason AR, Culver B, Ren J. Inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) differentially regulates contractile function in cardiac myocytes from normotensive and spontaneously hypertensive rats: role of Ca2+ regulatory proteins. Cell. Biochem. Biophys. 42: 1-12, 2005.

Li SY, Liu Y, Sigmon VK, McCort A, Ren J. High fat diet enhances advanced glycation endproduct (AGE) and apoptosis: Role of nuclear O-GlcNAc modification and p38 MAP kinase activation. Diabetes Obese. Metab. 7: 448-454, 2005.

Wold LE, Dutta K, Mason MM, Ren J, Cala SE, Schwanke ML, Davidoff AJ. Impaired SERCA function contributes to cardiomyocyte dysfunction in insulin resistant rats. J. Mol. Cell. Cardiol. 39:297-307, 2005.

Wold LE, Aberle II NS, Ren J. Doxorubicin induces cardiomyocyte dysfunction via a p38 MAP kinase-dependent oxidative stress mechanism. Cancer Detect. Prev.  29: 294-299, 2005.

Yang X, Palanichamy K, Ontko AC, Rao MNA, Fang CX, Ren J, Sreejayan N. A newly synthetic chromium complex - chromium (phenylalanine)3 improves insulin responsiveness and reduces whole body glucose tolerance. FEBS Lett 579: 1458-1464, 2005.

Yang X, Zhu MJ, Sreejayan N, Ren J, Du M. Angiotensin II promotes smooth muscle cells proliferation and migration through EGF-receptor pathway. Molecules Cells 20:263-270, 2005.

Zhang X, Dong F, Ren J, Driscoll MJ, Culver B. High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex. Exp. Neurol. 191:318-325, 2005.

Zhang X, Dong F, Li Q, Borgerding AJ, Klein AL, Ren J. Cardiac overexpression of catalase antagonizes ADH-associated exacerbation of contractile depression and stress signaling following acute ethanol exposure in murine myocytes. J. Appl Physiol. 99:2246-2254, 2005.

Ceylan-Isik AF, Ren J. Gender difference in cardiac excitation-contraction coupling: Role of estrogen. Cardiol. 1:1-7, 2005.

McBride SM, Flynn FW, Ren J. Cardiovascular alteration and treatment of hypertension: Do men and women differ? Endocrine 28:199-208, 2005.

Muralikrishnan D, Ren J. The emerging role of coenzyme Q-10 in aging, neurodegeneration, cardiovascular disease, cancer and diabetes mellitus. Curr. Neurovasc. Res. 2: 447-459, 2005.

Ren J, Fang CX. Small guanine nucleotide-binding protein Rho and myocardial function. Acta Pharmacologica Sinica 26:279-285, 2005.

Wold LE, Ceylan-Isik AF, Ren J. Oxidative stress and stress signaling: the menace of diabetic cardiomyopathy. Acta Pharmacologica Sinica 26:908-917, 2005.

Yang X, Sreejayan N, Ren J. Views from within and beyond: narratives of cardiac contractile dysfunction under senescence. Endocrine 26:127-138, 2005.

Aberle NS II, Lee KJ, Ren J. Korean anti-inflammatory compound Allergina enhances cardiac contractile function in isolated ventricular cardiomyocytes. J. Alter. Comp. Med. 10:514-518, 2004.

Aberle NS II, Picklo MJ Sr., Amarnath V, Ren J. Inhibition of cardiac myocyte contraction by 4-hydroxy-trans-2-nonenal. Cardiovasc. Toxicol. 4: 21-28, 2004.

Aberle II NS, Burd L, Zhao BH, Ren J. Acetaldehyde-induced cardiac contractile dysfunction may be alleviated by vitamin B1 but not vitamin B6 or vitamin B12. Alcohol Alcoholism 39: 450-454, 2004.

Dai S, Duan J, Lu Y, Zhang Y, Cheng J, Zhao X, Ren J, Wu Y, Ge Q, Wu Y. Phytoestrogen α-Zearalanol inhibits the progression of atherosclerosis and improves lipid profile in ovariectomized cholesterol-fed rabbits. Endocrine 25:121-130, 2004.

Davidoff AJ, Mason MM, Davidson MB, Carmody MW, Hintz KK, Wold LE, Podolin DA, Ren J. Sucrose-induced cardiomyocyte dysfunction is both preventable and reversible with clinically relevant treatments. Am. J. Physiol. Endo. Metab. 286: E718-E724, 2004.

Davidoff AJ, Davidson MB, Carmody MW, Davis ME, Ren J. Diabetic cardiomyocyte dysfunction coupled to myocyte insulin resistance: Role of glucose-induced PKC activity. Mol. Cell. Biochem. 262:155-163, 2004.

Duan J, Esberg LB, Dai S, Aberle NS II, Ren J. Comparison cardiac contractile and intracellular Ca2+ transient response between estrogen and phytoestrogen α-Zearalanol in rat ventricular myocytes. Endocrine 24:33-38, 2004.

Esberg LB, Ren J. The oxygen radical generator pyrogallol impairs cardiomyocyte contractile function via a superoxide and p38 MAP kinase-dependent pathway: Antagonism from anisodamine and tetramethylpyrazine. Cardiovasc. Toxicol. 4:375-384, 2004.

Esberg LB, Zhang X, Scott GI, Culver B, Ren J. Impact of gender on basal and insulin-like growth factor I (IGF-1)-regulated nitric oxide synthase activity in adult rat ventricular myocytes. Comp. Biochem. Physiol. 138:141-146, 2004.

Hintz KK, Ren J. Phytoestrogenic isoflavones daidzein and genistein reduce glucose toxicity-induced cardiac contractile dysfunction in ventricular myocytes. Endo. Res. 30:215-223, 2004.

Klein AL, Wold LE, Ren J. The cyclooxygenase-2 product prostaglandin E2 modulates cardiac contractile function in adult rat ventricular cardiomyocytes. Pharmacol. Res. 49:99-103, 2004.

Li SY, Gomelski M, Duan J, Zhang Z, Gomelski L, Zhang X, Epstein PN, Ren J. Overexpression of aldehyde dehydrogenase-2 transgene attenuates acetaldehyde-induced apoptosis in human umbilical vein endothelial cells: Role of ERK and p38 MAP kinase. J. Biol. Chem. 279:11244-11252, 2004.

Norby FL, Aberle NS II, Kajstura J, Anversa P, Ren J. Transgenic overexpression of insulin-like growth factor I prevents streptozotocin-induced cardiac contractile dysfunction and β-adrenergic response in ventricular myocytes. J. Endocrinol. 180: 175-182, 2004.

Ren J, Porter JE, Wold LE, Aberle NS II, Muralikrishnan D, Haselton JR. Depressed contractile function and adrenergic responsiveness of cardiac myocytes in an experimental model of Parkinson disease, the MPTP-treated mouse. Neurobiol Aging. 25: 131-138, 2004.

Ren J, Zhang X, Scott GI, Esberg LB, Ren BH, Culver B, Chen AF. Adenovirus gene transfer of recombinant eNOS enhances contractile function in ventricular myocyte. J. Cardiovasc. Pharm. 43: 171-177, 2004.

Wang GJ, Liao JF, Hintz KK, Chen WP, Su MJ, Lin YL, Shi CC, Chen CF, Ren J. Calcium-antagonizing activity of S-petasin, a hypotensive sesquiterpene from Petasites formosanus, on the inotropic and chronotropic responses in isolated rat atria and cardiac myocytes. Naunyn Schmiedeberg Arch Pharmacol. 369: 322-329, 2004.

Wold LE, Ren J. Streptozotocin directly impairs cardiac contractile function in isolated ventricular myocytes: Role of p38 MAP kinase pathway. Biochem. Biophys. Res. Comm. 318:1066-1071, 2004.

Xu HS, Duan J, Dai S, Wu YQ, Sun RY, Ren J. Phytoestrogen α-Zearalanol antagonizes oxidized LDL-induced inhibition of nitric oxide production and stimulation of endothelin-1 release in human umbilical vein endothelial cells. Endocrine 25:235-246, 2004.

Xu P, Tang H, Li SY, Ren J, Van Kirk E, Murdoch WJ, Radosz M, Shen Y. Enhanced stability of core-surface cross-linked micelles fabricated from Amphiphilic brush copolymers. Biomacromolecules 5: 1736-1744, 2004.

Book Chapters and Reviews

Dai S, Duan J, Lu Y, Cheng J, Ren J, Deng W, Wu Y. α-Zearalanol, a phytoestrogen for cardiovascular therapy. Endocrine 25:117-120, 2004.

Ren J. Leptin and hyperleptinemia – from friend to foe for cardiovascular function. J. Endocrinol. 181: 1-10, 2004.

Zhang X, Li SY, Brown RA, Ren J. Ethanol and acetaldehyde in alcoholic cardiomyopathy – from bad to ugly en route to oxidative stress. Alcohol. 32: 175-186, 2004.

Zheng JS, Lin L, Ren J, Chen AF. Tetrahydrobiopterin and endothelial dysfunction. Prog. Physiol. Sci. 35:155-158, 2004.

Aberle NS II, Ren J. Short-term acetaldehyde exposure depresses ventricular myocyte contraction: role of cytochrome P450 oxidase, xanthine oxidase, and lipid peroxidation. Alcohol Clin. Exp. Res. 27:577-583, 2003.

Aberle NS II, Privratsky JR, Burd L, Ren J. Combined acetaldehyde and nicotine exposure depresses cardiac contraction in ventricular myocytes: Prevention by folic acid. Neurotoxicol. Teratol. 25: 731-736, 2003.

Aberle NS II, Hiramatsu M, Ren J. Japanese herbal medicine Toki-Shakuyaku-San (TJ-23) enhances cardiac contractile function in isolated ventricular myocytes via a Na+/K+-ATPase-dependent mechanism. J Pharmacol Sci 91:197-201, 2003.

Duan J, Esberg LB, Ye G, Borgerding AJ, Ren BH, Aberle II NS, Epstein PN, Ren J. Influence of gender on ethanol-induced ventricular myocyte contractile depression in transgenic mice with cardiac overexpression of alcohol dehydrogenase. Comp. Biochem. Physiol. 134: 607-614, 2003.

Duan J, Zhang HY, Adkins SD, Ren BH, Norby FL, Zhang X, Benoit JN, Epstein PN, Ren J. Impaired cardiac contractile function and IGF-1 Response in myocytes from calmodulin diabetic mice: Role of Akt and RhoA. Am J Physiol Endocrinol Metab 284: E366-E376, 2003.

Esberg LB, Wang GJ, Lin YL, Ren J. Iso-S-Petasin, a hypotensive Sesquiterpene from Petasites Formosanus, depresses cardiac contraction and intracellular Ca2+ transients in adult rat ventricular myocytes. J Pharmacy Pharmacol 55: 103-107, 2003.

Esberg LB, Ren J. Role of nitric oxide, tetrahydrobiopterin and peroxynitrite in glucose toxicity-associated contractile dysfunction in ventricular myocytes. Diabetologia 46:1419-1427, 2003.

Folden DV, Gupta A, Sharma AC, Li S, Saari JT, Ren J. Malondialdehyde inhibits cardiac contractile function in ventricular myocytes via a p38 mitogen-activated protein kinase-dependent mechanism. Br. Pharmacol. 139: 1310-1316, 2003.

Hintz KK, Relling DP, Saari JT, Borgerding AJ, Duan J, Ren BH, Kato K, Epstein PN, Ren J. Cardiac over-expression of alcohol dehydrogenase exacerbates cardiac contractile dysfunction, lipid peroxidation and protein damage following chronic ethanol ingestion. Alcohol Clin. Exp. Res. 27:1090-1098, 2003.

Hintz KK, Aberle NS II, Ren J. Insulin resistance induces hyperleptinemia, cardiac contractile dysfunction but not cardiac leptin resistance in ventricular myocytes. International J. Obesity 27: 1196-1203, 2003.

Hintz KK, Ren J. Tetramethylpyrazine elicits disparate responses in cardiac contraction and intracellular Ca2+ transients in isolated adult rat ventricular myocytes. Vasc. Pharmacol. 40:213-217, 2003.

Privratsky JR, Wold LE, Sowers JR, Quinn MT, Ren J. AT1 blockade prevents glucose toxicity-induced cardiac dysfunction in ventricular myocytes: Role of the AT1 receptor and NADPH oxidase. Hypertension 42: 206-212, 2003.

Relling DP, Hintz KK, Ren J. Acute exposure of ceramide enhances cardiac contractile function in isolated ventricular myocytes. Br. J. Pharmacol. 140:1163-1168, 2003.

Ren J. Paradoxical effects of pyruvate on cardiac contractile function under normal and high glucose in ventricular myocytes. Pharmacol. Res 48: 25-29, 2003.

Ren J, Duan J, Hintz KK, Ren BH. High glucose induces cardiac insulin-like growth factor I resistance in ventricular myocytes: Role of Akt and ERK activation. Cardiovasc Res. 57: 738-748, 2003.

Ren J, Roughead ZK, Norby FL, Rakoczy S. Wold LE, Mabey RL, Brown-Borg HM. Increases in insulin-like growth factor-1 level and peroxidative damage after gestational ethanol exposure in rats. Pharmacol. Res. 47: 341-347, 2003.

Ren J, Wen YY, Hintz KK. Cardiac contractile response of human erythrocyte-derived depressing factor in ventricular myocytes from spontaneously hypertensive rats. J. Hypertens. 21:1183-1190, 2003.

Shavali S, Ren J, Ebadi M. Insulin-like growth factor-1 protects human dopaminergic SH-SY5Y cells from Salsolinol-induced toxicity. Neurosci Lett 340:79-82, 2003.

Wold LE, Muralikrishnan D, Albano CB, Norby FL, Ebadi M, Ren J. Insulin-like growth factor I (IGF-1) supplementation prevents diabetes-induced alterations in coenzyme Q-9 and Q-10. Acta Diabetologia. 40: 85-90, 2003.

Ye G, Metreveli NS, Ren J, Epstein PN. Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production. Diabetes 52:777-783, 2003.

Zhang X, Klein AL, Aberle NS II, Norby FL, Ren BH, Duan J, Ren J. Cardiac-specific overexpression of catalase rescues ventricular myocytes from ethanol-induced contractile defect. J. Mol. Cell. Cardiol. 35: 645-652, 2003.

Zhang X, Ye G, Duan J, Chen AF, Ren J. Influence of gender and age on cardiac contractile function in isolated ventricular myocytes from calmodulin-induced transgenic diabetic mice. Endocrine Res. 29: 227-236, 2003.

Zhang X, Wen YY, Xu XR, Dong F, Ren J. Agonist-stimulated Ca2+ transport in mesenteric vascular smooth muscle cells of vitamin D3-induced calcium overload rats. Vasc. Pharmacol. 40: 189-195, 2003.

Aberle NS II, Ren J. Experimental assessment of the role of acetaldehyde in alcoholic cardiomyopathy. Biol Proc Online 5:1-12, 2003.
 
Li SY, Culver B, Ren J. The benefit and risk of exercise on myocardial function in diabetes. Pharmacol. Res. 48: 127-132, 2003.

Dong F, Ren J. Insulin-like growth factors (IGFs) and IGF-binding proteins in nephrotic syndrome children on glucocorticoid. Pharmacol. Res. 48: 319-323, 2003.

Brown RA, Ilg KJ, Chen AF, Ren J. Dietary Mg2+ supplementation restored impaired vasoactive responses induced by chronic ethanol consumption in isolated rat aorta. Eur J Pharmacol. 442: 241-250, 2002.

Brown RA, Ilg KJ, Ren J. Influence of hypertension on tetrahydropapaveroline-induced vasorelaxation in rat thoracic aorta. Endocrine Res 28: 19-26, 2002.

Colligan PB, Brown-Borg HM, Duan J, Ren BH, Ren J. Cardiac contractile function is enhanced in isolated ventricular myocytes from growth hormone transgenic mice. J Endocrinol 173: 257-264, 2002.

Colligan PB, Relling DP, Ren J. Ceramide reduces high glucose-induced diabetic cardiomyopathy in adult rat ventricular myocytes.  Cell Mol. Biol. 48: OL251-OL257, 2002 (DOI 10.1170/31).

Duan J, McFadden GE, Borgerding TJ, Norby FL, Ren BH, Ye G, Epstein PN, Ren J. Over-expression of alcohol dehydrogenase exacerbates ethanol-induced contractile defects in cardiac myocytes. Am J Physiol Heart Circ Physiol. 282: H1216-H1222, 2002.

Golden KL, Ren J, Dean A, Marsh JD. Norepinephrine regulates the in vivo expression of the L-type calcium channel. Mol. Cell. Biochem. 236: 107-114, 2002.

Hintz KK, Ren J. Prediabetic insulin resistance is not permissive to the development of cardiac resistance to insulin-like growth factor I in ventricular myocytes. Diabetes Res. Clin Pract. 55: 89-98, 2002.

Hintz KK, Norby FL, Duan J, Cinnamen M, Doze VA, Ren J. Comparison of cardiac excitation-contraction coupling in isolated ventricular myocytes between rat and mouse. Comp. Biochem. Physiol. 133: 191-198, 2002.

Norby FL, Ren J. Anisodamine inhibits cardiac contraction and intracellular Ca2+ transients in isolated adult rat ventricular myocytes. Eur. J. Pharmacol. 439: 21-25, 2002.

Norby FL, Wold LE, Duan J, Hintz KK, Ren J. IGF-1 attenuates diabetes-induced cardiac contractile dysfunction in ventricular myocytes. Am J Physiol Endocrinol Metab 283:E658-E666, 2002.

Ren J, Brown-Borg HM. Impaired cardiac excitation-contraction coupling in ventricular myocytes from Ames dwarf mice with growth hormone/insulin-like growth factor I deficiency. Growth Horm IGF Res 12: 99-105, 2002.

Ren J, Ren BH, Sharma A. Sepsis-induced depressed contractile function of isolated ventricular myocytes is due to altered calcium transient properties. Shock 18: 285-288, 2002.

Ren J, Wang GJ, Petrovski P, Ren BH, Brown RA. Influence of hypertension on acetaldehyde-induced vasorelaxation in rat thoracic aorta. Pharmacol. Res. 45 195-199, 2002.

Ren J. Influence of genetically-predisposed diabetes on ethanol-induced depression of cardiac contraction in adult rat ventricular myocytes. Exp. Physiol. 87: 293-298, 2002.

15.    Ren J, Wold LE, Natavio M, Ren BH, Hannigan JH, Brown RA. Influence of prenatal alcohol exposure on myocardial contractile function in adult rat hearts: Role of intracellular Ca2+ and apoptosis. Alcohol Alcoholism 37: 30-37, 2002.

Ren J, Davidoff AJ. α2- Heremans Schmid Glycoprotein, a putative inhibitor of tyrosine kinase, prevents glucose toxicity associated with cardiomyocyte dysfunction. Diab Metab Rev Res 18: 305-310, 2002.

Ren J. Short-term administration of insulin-like growth factor I (IGF-1) does not induce IGF-1 resistance in hearts Growth Horm IGF Res 12: 162-168, 2002.

Turcotte L-A, Alberle NS II, Norby FL, Wang GJ, Ren J. Influence of prenatal alcohol exposure on vascular contractile response in rat thoracic aorta. Alcohol. 26: 75-81, 2002.

Wang GJ, Wu XC, Lin YL, Ren J, Lee CK, Chen CF. Calcium channel blocking effect of iso-S-petasin, a hypotensive sesquiterpene from Petasites Formosanus, in rat aortic smooth muscle cells. Eur. J. Pharmacol 445: 239-245, 2002. 

Wold LE, Relling DP, Norby FL, Duan J, Ren J. Abrogated leptin-induced cardiac contractile response in ventricular myocytes under spontaneous hypertension: role of Jak/STAT pathway. Hypertension 39: 69-74, 2002. 

Brown RA, Anthony MJ, Petrovski P, Ren J. Influence of gender, diabetes and acetaldehyde on intrinsic contractile properties of isolated rat myocardium. Cardiovasc. Toxicol. 1: 35-42, 2001.

Brown RA, Petrovski P, Savage AO, Ren J. Influence of ATP-sensitive K+ channel modulation on the mechanical properties of diabetic myocardium. Endocrine Res. 27: 269-281, 2001.

Brown RA, Walsh MF, Ren J. Influence of diabetes and gender on vascular and myocardial contractile function. Endocrine Res. 27: 399-408, 2001.

Golden KL, Ren J, O'Connor JA, Dean A, DiCarlo SE, Marsh JD. In vivo regulation of Na/Ca exchanger expression by adrenergic effectors. Am. J. Physiol. Heart Circ Physiol. 280: H1376-H1382, 2001.

Hintz KK, Wold LE, Colligan PB, Scott GI, Lee KJ, Sowers JR, Ren J. Influence of ovariectomy on ventricular myocyte contraction in simulated diabetes. J Biomed Sci 8: 307 – 313, 2001.

Ren J, Natavio M, Jefferson L, Pavlik ML, Brown RA. Loss of cardiac contractile response to tetrahydropapaveroline with advanced age and hypertension. Cell. Mol Biol. 47: OL15-22, 2001. (DOI 10.1170/3).

Scott GI, Colligan PB, Ren BH, Ren J. Ginsenosides Rb1 and Re inhibit cardiac contraction in ventricular myocytes: Role of nitric oxide. Br. J. Pharmacol. 134: 1159-1165, 2001.

Wang GJ, Shum AYC, Lin YL, Liao JY, Wu XC, Ren J, Chen CF. Calcium channel blockade by S-petasin, a hypotensive sesquiterpene from Petasites formosanus, in vascular smooth muscle cells. J Pharmacol Exp Ther 297: 240-246, 2001.
 
Wold LE, Norby FL, Hintz KK, Colligan PB, Epstein PN, Ren J. Prenatal alcohol exposure induces cardiac contractile dysfunction in offspring of rats: influence of maternal dietary Mg2+ supplementation. Cardiovasc. Toxicol. 1: 215-224, 2001.
 
Wold LE, Relling DP, Colligan PB, Scott GI, Hintz KK, Ren BH, Epstein PN, Ren J. Characterization of contractile function in diabetic hypertensive cardiomyopathy in adult rat ventricular myocytes. J. Mol. Cell. Cardiol. 33: 1719-1726, 2001.
 
Wold LE, Saari JT, Ren J. Isolated ventricular myocytes from copper–deficient rat hearts exhibits enhanced cardiac contractile function. Am. J. Physiol. Heart Circ Physiol. 281: H476-H481, 2001.

Book Chapters and Reviews

Ren J. Chinese herbal medicine in cardiovascular system: Looking through the mirror. North Dakota Academy of Science. 55: 30-32, 2001. 

Ren J. Diabetic cardiomyopathy and associated heart diseases: from bench to bedside. Adv. Cardiovasc. Disease 22: 299-302, 2001.

Ren J, Wold LE. Measurement of cardiac mechanical function in isolated ventricular myocytes from rats and mice by computerized video-based imaging. Biol. Proc. Online 3: 43-53, 2001.

Golden KL, Fan QI, Chen B, Ren J, O’Connor JA, Marsh JD. Adrenergic stimulation regulates Na+/Ca2+ exchanger expression in rat cardiac myocytes. J. Mol. Cell. Cardiol. 32: 611-620, 2000.

Nickola MW, Wold LE, Colligan PB, Wang GJ, Samson WK, Ren J. Leptin attenuates cardiac contraction in adult rat ventricular myocytes: Role of nitric oxide. Hypertension 36: 501-505, 2000

Ren J, Bode AM. Altered cardiac excitation-contraction coupling in ventricular myocytes from spontaneously diabetic BB rats. Am. J. Physiol. Heart Circ Physiol. 279: H238-244, 2000.

Ren J, Brown RA. Influence of chronic alcohol ingestion on acetaldehyde-induced depression of cardiac contractile function. Alcohol Alcoholism 35:554-560, 2000.

Ren J, Smude BW, Pavlik ML, Brown RA. Diminished cardiac inotropism of tetrahydropapaveroline in spontaneously hypertensive rats: role of beta-receptors. Alcohol 21: 149-159, 2000. 

Ren J, Sowers JR, Walsh MF, Brown RA. Reduced contractile response to insulin and insulin-like growth factor I in ventricular myocytes from genetically obese Zucker rats. Am. J. Physiol. Heart Circ Physiol. 279: H1708-1714, 2000.

Ren J, Walsh MF, Jefferson L, Natavio M, Ilg KJ, Sowers JR, Brown RA. Cardiac contractile response to ethanol in lean and obese Zucker rat hearts. J. Biomed. Sci. 7: 390-400, 2000.

Ren J, Wold LE, Epstein PN. Diabetes enhances acetaldehyde-induced depression of cardiac myocyte contraction. Biochem. Biophys. Res. Comm. 269: 697-703, 2000.

Ren J. Attenuated cardiac contractile responsiveness to insulin-like growth factor I in ventricular myocytes from biobreeding spontaneous diabetic rats. Cardiovasc. Res. 46: 162-171, 2000.

Book Chapters and Reviews

Ren J, Ren BH, Zhang XC, Wen YY. Insulin-like growth factor I (IGF-1) and cardiovascular aging. Chin. J. Geriatrics. 19: 468-488, 2000.