Skip to Main Navigation. Each navigation link will open a list of sub navigation links.

Skip to Main Content

Apply to the University of Wyoming

Global Resource Navigation

Give to UW
Download UW Viewbook
Visit Campus

UW Technologies Available for Licensing

Wyoming Research Products Center

Charge Reversible Polymers

 

Description of Technology:

This technology relates to charge reversible polymers, peptides and their resulting colloidal particles. Their primary and secondary amines are protected as easily hydrolysable amides. The amides are relatively stable at neutral pH but quickly hydrolyze at low pH. These polymers, peptides or particles are thus charge-reversible: at neutral pH they are negatively charged but become positively charged at acidic pH.

Applications:

Charge Reversible Polymers can be developed for use as drug delivery carriers to solid tumors and lysosomes. Charge Reversible Polymers can also be used as gene delivery carriers, as well.

Features and Benefits:

This technology, as a drug delivery carrier, will be able to localize and directly release drugs into the nucleus of a cell and would circumvent the multi-drug resistance and intracellular drug-resistance to effectively deliver drugs to the vicinity of DNA, leading to high therapeutic efficacy.

For More Information Please Contact:

Davona Douglass, J.D.
Director
(307) 766-2509
dkdoug@uwyo.edu

Tech ID

06-105

Inventors

Xu, Peisheng

Patent Status

Filed - US Patent Application

Share This Page:

1000 E. University Ave. Laramie, WY 82071
UW Operators (307) 766-1121 | Contact Us | Download Adobe Reader

Twitter Icon Youtube Icon Instagram Icon Vimeo Icon Facebook Icon

Accreditation | Emergency Preparedness | Employment at UW | Gainfull Employment | Privacy Policy | Accessibility Accessibility information icon