Methods for Natural Antibiotic Product Optimization

Description of Technology:

This technology utilizes the predatory behavior of myxobacteria to select optimized antibiotic producing strains. The result is the rapid chemical optimization of natural product antibiotics including antibiotics and anti-fungals produced by microorganisms.

Applications:

Methods for Natural Antibiotic Product Optimization can be used to find pre-clinical drug candidates that have therapeutic utility.

Features and Benefits:

This technology has the ability to revolutionize strain optimization when compared to classical laborious screens. Traditional methods rely on screens – this technology utilizes the myxobacteria’s predatory nature to target prey cells that can be used for selection to isolate novel lead compounds that are active on clinically relevant pathogens.

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