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UW Technologies Available for Licensing|Wyoming Research Products Center

Resistance to Viruses and Viroids in Transgenic Plants and Animals Expressing dsRNA-Binding Protein


Description of Technology:

The invention provides a method for imparting resistance in animals to viruses, and in plants to viruses and viroids, that express double-stranded RNA-like structures (dsRNAs). The presence of a dsRNA-binding protein in a transgenic host renders the transgenic host resistant to the phenotypic replication.

Applications:

This method enables the binding of pathogenic dsRNA-binding protein in transgenic animal and plant hosts, thus interrupting the infection cycle and inhibiting disease.

Features and Benefits:

This invention provides a genetically engineered animal and plant, stably transformed to express a dsRNA-binding protein, such that the transgenic host displays resistance to virus and/or viroid challenge.

For More Information Please Contact:

Davona Douglass, J.D.
Director
(307) 766-2509
dkdoug@uwyo.edu

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Tech ID

95-002

Inventors

Patent Status

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