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R. Scott Seville, Principal Investigator/ Program Director

338 Wyo Hall, 1000 E. University Ave.

Laramie, WY 82071

Phone: (307) 277-3106

Email: sseville@uwyo.edu

Wyoming INBRE Logo
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Wyoming INBRE

Developmental Research Project Program

The Developmental Research Project Program (DRPP) is a new mandatory component for INBRE 3 with a goal to select and support the most promising research within the Wyoming INBRE scientific themes of “cardiometabolic syndrome” and “technology for chronic disease research and therapeutics”. Our goal is to augment and strengthen the Network by providing research opportunities to faculty and students and requiring standards for research excellence. Both themes tackle rather significant health issues in the State of Wyoming and the INBRE goal is to build a collaborative interdisciplinary research team to develop and apply new targets and tools to address intractable biomedical problems. The DRPP is required to: 1) provide an internal mechanism (internal Funding Opportunity Announcement) for obtaining and awarding multidisciplinary developmental research projects, 2) review and prioritize those projects for funding, 3) develop a plan for their general mentoring, and 4) offer oversight, and evaluation, as well as assure their full compliance with all applicable federal policies, rules, and guidelines for research involving human subjects, vertebrate animals, and/or biohazards. The DRPP offers several mechanisms to foster research collaborations between the lead and partner PUI institutions. To overcome the major barriers for PUI researchers due to being isolated in their research and lack of institutional support for research in a PUI environment where teaching is the primary responsibility, we will increase resources allocated to PUIs and facilitate collaboration between INBRE funded UW investigators and PUI faculty by increasing the number of collaborative grants available, requiring UW investigators to dedicate 10% of their award to PUI collaboration, and increasing the number of INBRE Network workshops, trainings and networking events to increase cross network interaction. The DRPP has established an internal mechanism for soliciting grant applications, reviewing and prioritizing applications. The DRPP offers a plan for general mentoring, career development, faculty retention, and evaluation, as well as assurance in compliance with all applicable federal policies, rules, and guidelines. These approaches provide a step-by-step mechanism to better engage PUI faculty and students into biomedical research and foster career development of junior investigators for competitive research across the network.

David Fay, Ph.D.
INBRE Developmental Research Projects Program Director
Professor of Molecular Biology 
Office: (307) 766-766-4961; Lab: (307) 766-4962; FAX: (307) 766-5098
davidfay@uwyo.edu

Types of Research Proposals and Awards

Thematic Project Research Proposals and Awards: Compete every other year; 
  • Target RFA population: tenure-track assistant professors; 

  • Focused studies that fit within Wyoming INBRE thematic research areas “Cardiometabolic syndrome” and “Technology for chronic disease research and therapeutics”;

  • Amount: Up to $75K per year for 2-3 years;

  • Can be independent or collaborative projects ($$ remain in IDeA states);

  • Publish in each year of the award;
  • Expected to submit NIH R-type grant at the end of two years;

  • 10% of budget allocated to the PUI collaboration.

Pilot Project Research Proposals and AwardsCompete every other year;
  • No specific target population for application, faculty at all ranks;
  • Studies that can be broadly defined as biomedical or behaviour studies;
  • Amount: Up to $25K per year for 2 years;

  • Can be independent or collaborative projects ($$ remain in IDeA states);

  • Expected to submit NIH R-type grant at the end of two years;

  • 10% of budget allocated to the PUI collaboration.

Proposals and Awards to Support Graduate Students: Compete every year;
  • Support promising PhD students, usually after passing qualifying exams;
  • No specific target population for faculty advisor, faculty at all ranks;

  • Studies that can be broadly defined as biomedical or behaviour studies;

  • Amount: the standard PhD stipend scale, plus tuition and fees (typically provided by University of Wyoming academic affairs as a part of institutional support) for 1-2 years;

  • Expected to present at national conference and publish 1 peer-reviewed article;

  • Commitment to interacting with PUIs as seminar speaker, undergraduate student mentor, etc.

University of Wyoming-PUI Collaborative Research AwardsCompete every other year;
  • Target University of Wyoming and PUI faculty:

  • Studies that can be broadly defined as biomedical or behaviour studies;

  • Amount: $20,000/year to be shared by UW and PUI collaborators. Focus on enhancing research at PUI, enhancing undergraduate student pipeline between college and university, and increasing access to research infrastructure at UW for college faculty;

  • Expected to present at national conference and/or publish peer-reviewed articles;

  • Plan to seek external funding to sustain project and pipeline activities beyond two-year award.

Current Awards:

Thematic Research Projects
  1. Rebecca Carron, Assistant Professor School of Nursing. POLYCYSTIC OVARIAN SYNDROME IN AMERICAN INDIAN WOMEN: AN EXPLORATORY STUDY.

  2. Brian Cherrington, Assistant Professor Zoology and Physiology. The Effect of Obesity Induced Hyperinsulinemia on Lactation.

  3. Wei Guo, Assistant Professor Animal Sciences. ROLE OF RBM20 IN THE REGULATION OF CARDIAC GENE SPLICING IN HEART FAILURE.

  4. Guanglong He. Associate Professor School of Pharmacy. CARD9 Signaling and Childhood Obesity-Associated Cardiac Dysfunction.

  5. Anya Lyuksyutova, Assistant Researcher, Molecular Biology. OPTOGENETIC CONTROL OF GCS VIA MICRORNAS AS TREATMENT FOR LIVER STEATOSIS.

  6. Amy Navratil, Assistant Professor Zoology and Physiology. MOLECULAR MECHANISMS OF LUTEINIZING HORMONE DYSREGULATION IN PCOS.

  7. John Oakey, Assistant Professor, Chemical Engineering. CIRCULATING TUMOR CELL CAPTURE AND RELEASE FROM DEGRADABLE HYDROGEL SURFACES.

  8. Christine Porter, Assistant Professor Kinesiology and Health. GROWING RESILIENCE PHASE II: ALBANY COUNTY REDESIGN AND WIND RIVER EXPANSIONS.

  9. Baskaran Thyagarajan. Assitant Professor School of Pharmacy. TRPV1 ACTIVATION PREVENTS FROM HIGH FAT DIET-INDUCED NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) IN OBESITY VIA SIRT-1.

Pilot Research Projects:
  1. Grant Bowman, Assistant Professor Molecular Biology. Genetic, Biophysical, and Structural Analysis of Network Connectivity at an ntrinsically Disordered Hub Protein Interface.

  2. Jared Bushman, Assistant Professor Pharmacy. Localized immunosuppression for peripheral nerve allografts.

  3. Carl Frick, Professor Electrical Engineering. Removable and Replaceable Glaucoma Treatment Device Pilot Study.

  4. Jason Gigley, Assitant Professor Molecular Biology. Transition Metal Chelators as Novel Therapeutics Against Toxoplasma gondii.

  5. Karen Gaudreault and Stacy Carling. Department of Kinesiology and Health. Healthy Pokes: a multi-disciplinary effort promoting healthy lifestyles in Wyoming children at risk for developing overweight and obesity.

  6. Dongmei (Katie) Li, Assistant Professor Chemical Engineering. Hydrogel nanoparticles for the encapsulation and delivery of diagnostic and therapeutic molecules.

Collaborative Research Projects:
  1. Eric Atkinson, Biology Northwest Wyoming College and Matt Carling, Assistant Professor Zoology and Physiology, UW. Which factors influence the distribution and impacts of diseases in wild birds?

  2. Bud Chew, Biology Western Wyoming Community College and Jun Ren, Professor Pharmacy, UW. Environmental Exposure and Cardiometabolic Syndrome.

  3. Ami Erickson, Biology Sheridan College and Sadanand Dhekney, Agricultural Experiment Research Station, UW. Studying Grapevine Cellular and Physiological Response to Abiotic Stress.

  4. Hayley Lanier, Assistant Professor Zoology and Physiology, UW Casper and Merav Ben-David, Professor of Zoology and Physiology, UW. Genomic assessment of the role of relatedness in spatial overlap in chipmunks.

  5. Steve McAllister, Biology Central Wyoming College and Baskaran Thyagarajan, Assistant Professor Pharmacy, UW. Analyses of mechanisms by which TRP protein activation protects from vascular dysfunctions in metabolic syndrome.

  6. Florence Teulé, Biology UW Casper and Patrick Johnson, Assistant Professor Chemical Engineering, UW. Generation of Electrospun Spider Silk Nanofiber Mats for Medical Applications.


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R. Scott Seville, Principal Investigator/ Program Director

338 Wyo Hall, 1000 E. University Ave.

Laramie, WY 82071

Phone: (307) 277-3106

Email: sseville@uwyo.edu

Wyoming INBRE Logo
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