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Zoology and Physiology|College of Arts and Sciences

Francis W. (Bill) Flynn
Professor
Director, Graduate Neuroscience Program


B.A. University of Colorado
Ph.D. Kansas State University
Post doctoral: University of Pennsylvania
flynn@uwyo.edu • 307-766-6446
     

I was born in East Meadow, Long Island NY. I left the east to attend the University of Colorado, Boulder- to ski and major (ultimately) in psychology. During my undergraduate education my interests focused on brain function and behavior, and there were a number of courses in Biopsychology available at CU. Courses in the Department of Molecular, Cellular, and Developmental Biology strengthened my overall biology background. After graduation I moved to Jackson Hole, Wyoming to ski. Undoubtedly one of the best ski areas in the world, and great access to Teton and Yellowstone Parks for summer trips. That was a great time with lasting memories and many close friendships were formed some of which continue today.

I lived and skied at Jackson for a couple of years and then spent a some time in Lookout Mountain, GA, just outside of Chattanooga before entering graduate school. I completed my Ph.D. in Neuroscience in 1981 and then took a position at the University of Pennsylvania with Dr. Harvey Grill in the Institute of Neurological Sciences. While at Penn I had the good fortune to receive additional training from Drs. Stellar and Epstein. My federal grant funding began at Penn and my research continues to be supported by grants from the National Institutes of Health. My research has addressed the neural and neurohormonal regulation of food intake (energy balance), blood pressure, and fluid balance. I accepted a position at the University of Wyoming in 1986 where I am the Director of the Neuroscience Training and a Professor of Physiology. I also serve as Director of the NIH Center of Biomedical Research Excellence in Neuroscience. Outdoor activities continue to be my passion and the area surrounding the University of Wyoming provides ample opportunity for skiing, fly fishing, and mountain biking. I've instilled an appreciation of the outdoors and activities in my two children, and my son introduced me to the joys (and pains) of downhill mountain biking. Overall, I like gravity sports! When not in Laramie, we are over in Steamboat Springs, CO., or traveling. My favorite country to visit is Australia and even after several trips (and part of a sabbatical) I look forward to another visit to "down under" (in spite of the flight!).
     

Research Interests:
Behavioral and neuroendocrine regulation of body fluid balance and osmolarity.
    

Publications:

REFEREED JOURNAL ARTICLES

McBride, S.M., Smith-Sonneborn, J., Oeltgen, P., and Flynn, F.W. (2005). Delta opiate receptor agonist facilitate mean arterial pressure recovery following hemorrhage in conscious rats. Shock, 23:264-268.

Haley, G.E. & Flynn, F.W. (2005). Agonist trafficking of NK3 receptor on vasopressinergic neurons. Abstracts Society for Neuroscience, 30.

Schamber, K.C., Lang, A.L., & Flynn, F.W. (2005). Neurokinin B transcript in the paraventricular nucleus of the hypothalamus is modulated by hyperosmolarity in rats. Abstracts Society for Neuroscience, 30.

Flynn, F.W. (2005). Intraventricular injections of tachykinin NK3 receptor agonist reduce the gain of the baroreflex in unrestrained rats. Experimental Neurology, 193: 118-124.

McBride, S.M., Culver, B., & Flynn, F.W. (2005). Prenatal and early postnatal salt experience affects motor responses to amphetamine in adult male WKY and SHR rats. Abstracts Society for Neuroscience, 30.

Adams, D.J., Haley, G., & Flynn, F.W. (2005). Repeated experience with sodium deficiency enhances salt intake and induces persistent c-Fos and Fos B expression in rat brain. Abstracts Society for Neuroscience, 30.

Jensen, D.D, Lang, A.L., & Flynn, F.W. (2005). Characterization of the neurokinin B promoter in rat. Abstracts Society for Neuroscience, 30.

Flynn, F.W., Culver, B, and Newton, S.V. (2003). Salt intake by spontaneously hypertensive rats. Physiology & Behavior, 78: 689-696.

Bealer, S.L. & Flynn, F.W. (2003). Central neurokinin 3 receptors increase systemic oxytocin release: Interaction with norepinephrine. Experimental Neurology, 184: 1027-1033.

Flynn, F.W. & Stricker, E.M. (2003). Hypovolemia stimulates intraoral water and NaCl intake in intact but not in chronic decerebrate rats. Physiology & Behavior, 80: 281-287.

Flynn, F.W., Kirchner, T.R., and Clinton, M. (2002). Brain vasopressin and salt appetite. American Journal of Physiology 282: R1236-R1244.

Flynn, F.W. (2002). Sodium deficiency enhances the behavioral responses to centrally administered vasopressin in rats. Peptides, 23: 1427-1432.

Flynn, F.W., Heyborne, R. & Dolence, K. (2001) Internalization of NK3 receptor agonist, senktide, following intraventricular injection in rat. Regulatory Peptides, 97, 47.

Flynn, F.W. (2000). Intraventricular injection of tachykinin NK3 receptor agonists suppress the ingestion of NaCl-associated tastes. Behavioral Neuroscience, 114, 1223-1228

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