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Week
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Topic
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Lecture
hand outs and materials (click on each talk) |
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1
first day of class)
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Overview
and review of basic cell structure, function and cell diversity in mammals |
L-1
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L2
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Equilibrium
of ions and anions cross cell membrane The nernst calculation (xls file) The Nernst Calculation: selected student's works |
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L3
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All you
need to know about Bioelectricity Down load the axon guid (large file!) |
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2
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Membrane
voltage-gated ion channels (part 1): molecular structure, biophysics |
L4
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Action potentials and methods for studying ion channels
Download Hodgkin Nobel lecture: The ionic basis of
nerve conduction (pdf formate) Dowload Erwin Neher Nobel Lecture: Ion channels for
communication between and within the cells |
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/L5
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Molecular
structure and classification of ion channels |
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L6
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3
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Membrane
voltage-gated ion channels (part 2): regulation of physiological and
pathological process |
Lab1
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L7
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Mechanisms
of ion channels block, toxins |
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L9
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Dysfunction
of ion channels and human disease: The Channelopathies |
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4
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Microscopy
theory and techniques, novel microscopy techniques |
L10
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The
light microscopes |
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L11
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L12
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5 |
Transport
across biological membranes: molecular structures, biophysics and regulation
of physiological and pathological process |
L13
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Novel
microscopy techniques
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L14
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Exam 1 :
Membrane channels and microscopy |
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L15
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Principals of transport cross cell membrane /ATPase NaK pump, Ca2+ pump and other membrane transporters |
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6
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Cell-to-cell
signaling (1): hormones, receptors and intracellular messengers |
L16
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Transporters: regulation of physiological and pathological process |
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L17
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Introduction
to signal transduction system |
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L18
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7
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Cell-to-cell
signaling (2) Physiology
and diseases |
L19
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L20
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L21
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Nobel
lecture: Paul Greengard, Neurobiology and dopaminergic signaling |
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8
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Protein
synthesis, vesicular trafficking, endocytosis and exocytosis |
L22
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The
"secrete" life of the cell: exocytosis and endocytosis |
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L23
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Advance
topics of endocytosis and exocytosis |
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L24
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Experimental
theory and techniques for studying hormone secretion |
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9
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Extracellular
matrix and cell-cell interactions |
L25
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Extracellular
matrix and cell interactions |
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L20
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Gap
junctions and cell functions |
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L27
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Exam 2: Second messengers and cell-cell intereractions The dates for exam to be annouce soon (October-31) |
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Ligand-gated
ion channels |
L28 |
Ligand-gated
ion channels1 |
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L29 |
Ligand-gated
ion channels 2 |
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L30 |
Neurons
and glia |
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12 |
Synaptic
transmission, and neuromuscular junction |
L31 |
Skeletal
muscle, Neuromuscular junction |
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L32 |
Cellular
mechanisms of Neurological disorders |
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L19
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13 |
Genetic
approaches to study the physiology of mammalian cell: |
L34 |
The central
Dogma, The human Genome project |
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L35 |
From
genome to mRNA (transcription) |
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L36 |
From
mRNA to protein (translation) |
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14 |
Aspects
of experimental techniques in cell physiology |
L37 |
Manipulating
Cells and Viruses in Culture |
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L38 |
Recombinant
DNA, Gene transfection and manipulation |
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L39 |
Protein
analysis (2D gel etc), Introduction to Proteomics |
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15
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Aspects
of experimental techniques in cell physiology (II) |
L40 |
Transgenic
animals, Animal Cloning and Stem cells |
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L41 |
TBD |
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L42 |
TBD |
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16 |
Final
exam |
L43 |
TBD |
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L44 |
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L45 |
Exame 3: Final
exam: Molecular physiology and selected topics in excitable cells |
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17 |
Student
Presentations (2) |
L46 |
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L47 |
A example of Student Presentation: Rich Jenkins |
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L48 |
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