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Resistance to Viruses and Viroids in Transgenic Plants and Animals Expressing dsRNA-Binding Protein

UW ID: 95-002

Description of Technology

          The invention provides a method for imparting resistance in animals to viruses, and in plants to viruses and viroids, that express double-stranded RNA-like structures (dsRNAs). The presence of a dsRNA-binding protein in a transgenic host renders the transgenic host resistant to the phenotypic replication. 


          This method enables the binding of pathogenic dsRNA-binding protein in transgenic animal and plant hosts, thus interrupting the infection cycle and inhibiting disease. 

Features and Benefits

          This invention provides a genetically engineered animal and plant, stably transformed to express a dsRNA-binding protein, such that the transgenic host displays resistance to virus and/or viroid challenge.

Downloadable PDF: 95-002


Roth, Don

Patent Status: 

Patent Issued

Contact Us: 

University of Wyoming Technology Transfer and Research Products Center 

Dept. 3672

1000 E. University Ave. 

Laramie, WY 


Phone: 307-766-2520

Fax: 307-766-2530

Contact Us

Wyoming Technology Transfer and Research Products Center

Dept. 3672

1000 E. University Ave.

Laramie, WY 82071

Phone: (307) 766-2520

Fax: (307) 766-2530


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