Therapeutic Strategy Using Capsaicin for Obesity Management

Applications

          Dietary capsaicin may be used by individuals looking for a non-invasive therapeutic treatment for abnormal body-weight gain. 

Features & Benefits

Dietary capsaicin may help individuals manage obesity by:

• Inhibiting weight gain

• Decreasing fat deposition/oil droplet accumulation in adipocytes

• Stimulating metabolic activity

• Increasing transcription factors that regulate adipogenesis and brown fat thermogenesis

• Increasing the expression of regulatory proteins in the body

• Increasing the mRNA and protein levels of bone morphogenetic proteins (BMP) and uncoupling proteins (UCP1 and UCP-2) and PGC-1alpha in white adipose tissue

• Increasing the genes/proteins that stabilize transcriptional factors 

Marketing Opportunity

          The obesity drug market in 2010 was $420 million; this market is expected to increase to $2.6 billion by 2020. Using therapeutic agents like dietary capsaicin, offers new business potential for developing pharmacotherapies and treatments to manage obesity. This product may have high revenue potential in the healthcare industry. Available pharmacotherapies, bariatric surgery and dietary modifications are not applicable for all patients, therefore it is important to develop robust and reliable pharmacotherapies to prevent and manage obesity and other complications including vascular dysfunction, hyperglycemia, diabetes, etc. 

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