Selected Publications

Department of Chemistry, University of Wyoming


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  1. Tristan F. Kinde, Thomas D. Lopez, Franco Basile, and Debashis Dutta, Electrophoretic Extraction of Low Molecular Weight Cationic Analytes from Sodium Dodecyl Sulfate Containing Sample Matrices for Their Direct Electrospray Ionization Mass Spectrometry, Anal. Chem. 2015, 87 (5), 2702−2709. DOI: 10.1021/ac503903j journal link: correction  article
  2. Tristan F. Kinde, Franco Basile, and Debashis Dutta, A Microfluidic SPLITT Device for Fractionating Low-Molecular Weight Samples, Anal. Chem. 2013, 85 (15), 7167−7172. DOI: 10.1021/ac400843s journal link: correction  article
  3. R. Mahat, S. Corrine, F. Basile, N. L. Ward, Global and targeted lipid analysis of Gemmata obscuriglobus reveals the presence of lipopolysaccharide, a     signature of the classical Gram-negative outer membrane, J. Bacteriology, 2016, 198, 221-236 journal link
  4. Rajendra Mahat, Wesley Rodgers, Franco Basile, Microwave Radiation Heating in Pressurized Vessels for the Rapid Extraction of Coal Samples for   Broad Spectrum GC–MS Analysis, Energy & Fuels, 2014, 28, 6326-6335 journal link
  5. Lu, L. and F. Basile, Thermal decomposition of phosphorylated peptides in the condensed phase as studied by mass spectrometry. Journal of            Analytical and Applied Pyrolysis, 2013, 104, 412-417 journal link
  6. Gwendoline M. Toh-Boyo, Shaun S. Wulff, Franco Basile, Comparison of Sample Preparation Methods and Evaluation of Intra and Intersample Reproducibility in Bacteria MALDI-MS Profiling, Anal. Chem. 2012, 84, 9971-9980 journal link
  7. Basile, F., Zhang, S., Kandar, S., Lu, L.,  Mass Spectrometry Characterization of the Thermal Decomposition/Digestion (TDD) at Cysteine in Peptides and Proteins in the Condensed Phase, J. Am. Soc. Mass Spectrom., 22 (2011) 1926-1940
  8. Chenglin Liu, Franco Basile, Intermolecular condensation products formed during the pyrolysis of peptides, J. Analytical and Applied Pyrolysis, 92 (2011) 217-223
  9. Basile, F., Hauser, N. J., Rapid Online Non-Enzymatic Protein Digestion Combining Microwave Heating Acid Hydrolysis and Electrochemical Oxidation, Anal. Chem., 2011, 83, 359-367. Journal link
  10. Basile, F.; Sibray, T.; Belisle, J.; Bowen, R., Analysis of Lipids from Crude Lung Tissue Extracts by Desorption Electrospray Ionization-MS and Pattern Recognition. Anal. Biochem. 2011, 408, 289-296
  11. Basile, F.; Zhang, S.; Shin, Y.-S.; Drolet, B., Atmospheric pressure-thermal desorption (AP-TD)/electrospray ionization-mass spectrometry for the rapid analysis of Bacillus spores. Analyst 2010, 135, (4), 797-803.
  12. Hauser, N.J. and F. Basile, On-line Microwave D-Cleavage LC-ESI-MS/MS of Intact Proteins: Site-Specific Cleavages at Aspartic Acid Residues and Disulfide Bonds. Journal of Proteome Research, 2008. 7: p. 1012-1026. PubMed abstract, Journal link
  13. Hauser, N., H. Han, S.A. McLuckey, and F. Basile, Electron Transfer Dissociation of Peptides Generated by Microwave D-cleavage Digestion of Proteins. J. Proteome Res., 2008. 7: p. 1867-1872. PubMed abstract
  14. Zhang, S., Y.-S. Shin, R. Mayer, and F. Basile, On-probe pyrolysis desorption electrospray ionization (DESI) mass spectrometry for the analysis of non-volatile pyrolysis products. Journal of Analytical and Applied Pyrolysis, 2007. 80(2): p. 353-359. Journal link
  15. Zhang, S. and F. Basile, Site-Specific Pyrolysis-Induced Cleavage at Aspartic Acid Residue in Peptides and Proteins. J. Proteome Res., 2007. 6(5): p. 1700-1704. PubMed abstract
  16. Shin, Y.-S., B. Drolet, R. Mayer, K. Dolence, and F. Basile, Desorption Electrospray Ionization-Mass Spectrometry of Proteins. Analytical Chemistry, 2007. 79(9): p. 3514-3518. PubMed abstract, Journal link
  17. Meetani, M.A., Y.-S. Shin, S. Zhang, R. Mayer, and F. Basile, Desorption electrospray ionization mass spectrometry of intact bacteria. Journal of Mass Spectrometry, 2007. 42(9): p. 1186-1193. PubMed abstract, Journal link
  18. Basile, F., G.E. Kassalainen, and S.K.R. Williams, Interface for Direct and Continuous Sample-Matrix Deposition onto a MALDI Probe for Polymer Analysis by Thermal Field Flow Fractionation and Off-Line MALDI-MS. Analytical Chemistry, 2005. 77(9): p. 3008-3012. PubMed abstract, Journal link
  19. Havey, C.D., F. Basile, C. Mowry, and K.J. Voorhees, Evaluation of a micro-fabricated pyrolyzer for the detection of Bacillus anthracis spores. Journal of Analytical and Applied Pyrolysis, 2004. 72(1): p. 55-61. Journal link
  20. Fung, K.Y.C., S. Askovic, F. Basile, and M.W. Duncan, A simple and inexpensive approach to interfacing high-performance liquid chromatography and matrix-assisted laser desorption/ionization-time of flight-mass spectrometry. Proteomics, 2004. 4(10): p. 3121-3127. PubMed abstract
  21. Basile, F., I. Ferrer, E.T. Furlong, and K.J. Voorhees, Simultaneous multiple substrate tag detection with ESI-ion trap MS for in vivo bacterial enzyme activity profiling. Analytical Chemistry, 2002. 74(16): p. 4290-4293. PubMed abstract
  22. Madonna, A.J., F. Basile, E. Furlong, and K.J. Voorhees, Detection of bacteria from biological mixtures using immunomagnetic separation combined with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Communications in Mass Spectrometry, 2001. 15(13): p. 1068-1074.
  23. Madonna, A.J., F. Basile, I. Ferrer, M.A. Meetani, J.C. Rees, and K.J. Voorhees, On-probe sample pretreatment for the detection of proteins above 15 KDa from whole cell bacteria by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Communications in Mass Spectrometry, 2000. 14(23): p. 2220-2229. Journal link
  24. Basile, F., M.B. Beverly, and K.J. Voorhees, Pathogenic bacteria: their detection and differentiation by rapid lipid profiling with pyrolysis mass spectrometry. TrAC, Trends in Analytical Chemistry, 1998. 17(2): p. 95-109. Journal link
  25. Basile, F., M.B. Beverly, C. Abbas-Hawks, C.D. Mowry, K.J. Voorhees, and T.L. Hadfield, Direct Mass Spectrometric Analysis of in Situ Thermally Hydrolyzed and Methylated Lipids from Whole Bacterial Cells. Analytical Chemistry, 1998. 70(8): p. 1555-1562. Journal link
  26. Beverly, M.B., F. Basile, K.J. Voorhees, and T.L. Hadfield, A rapid approach for the detection of dipicolinic acid in bacterial spores using pyrolysis/mass spectrometry. Rapid Commun. Mass Spectrom., 1996. 10(4): p. 455-58.
  27. Basile, F., K.J. Voorhees, and T.L. Hadfield, Microorganism gram-type differentiation based on pyrolysis-mass spectrometry of bacterial fatty acid methyl ester extracts. Applied and Environmental Microbiology, 1995. 61(4): p. 1534-9. Journal link



Book Chapters:

Basile F., Mignon R., "Methods and instrumentation in mass spectrometry for the differentiation of closely related microorganisms" in Applications of Mass Spectrometry in Microbiology, edited by Plamen Demirev and Todd Sandrin, Springer: 2016; pp. 13-50.

 Basile F., "Rapid Sample Preparation for Microorganism Analysis by Mass Spectrometry"  in Rapid Characterization of Microorganisms by Mass Spectrometry, ed.; Fenselau, C.; Demirev, P., Ed. American Chemical Society: 2011; pp 5-34.

Poster Presentations:

ASMS 2017  Characterization of the Lipid A Forms in Gemmata obscuriglobus by MALDI-ToF/ToF-MS, Rudolph Mignon ; Anthony Maus ; Rajendra Mahat ; Corrine Seebart ; Naomi Ward ; Franco Basile*, University of Wyoming, Laramie, WY

ASMS 2016   Differentiation of bacteria at the strain level by MALDI-MS of proteins >15kDa; Franco Basile* ; Bledar Bisha, Anthony Maus ,
University of Wyoming, Laramie, WY

ASMS2015  Code: MP05

(190) Liquid Chromatography Direct Electron Ionization Mass Spectrometry for the Analysis of Polycyclic Aromatic Hydrocarbons
Mitchell Helling; Franco Basile; University of Wyoming, Laramie, WY
ASMS2014  Code: TP32 Time Slot/Poster Number: 606 Session: Energy: Hydrocarbon and Petrochemical
(1683) Pressurized Heating for the Rapid Preparation/Extraction of Coal Samples for Broad Spectrum GC-MS Analysis
Franco Basile1; Rajendra Mahat1; Wesley Rodgers2; 1University of Wyoming, Laramie, WY; 2JR Simplot Co, Boise, ID

ASMS2014  Code: WP01   Session: Imaging MS: Sample Preparation

(1845) Photo-Thermal Decomposition/Digestion (Photo-TDD) of Proteins and its Application in MALDI-MS Imaging
Rong Zhou; Franco Basile; University of Wyoming, Laramie, WY

ASMS2013  Code: ThP25   Session: Microorganisms: Identification and Characterization
(2977) Differentiationof Borrelia species with MALDI-MS using spray sample deposition
Franco Basile1; Gwendoline Toh-Boyo1; Shaun Wulff1; Claudia Molins2; 1University of Wyoming, Laramie, WY; 2Centers for Disease Control and Prevention, Fort Collins, CO

ASMS2012  Code: WP09   Session: Microorganisms: Identification and Characterization

(2035) Evaluation of MALDI Intra Spot and Inter Sample Reproducibility in Bacteria Profiling with MALDI-MS
Franco Basile; Gwendoline Toh-Boyo; Shaun Wulff; University of Wyoming, Laramie, WY

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