University of Wyoming
Department of Chemistry

Kubelka Group
Protein Folding - Biomolecular Spectroscopy - Computational Chemistry

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Our research focuses on understanding the molecular mechanism of protein folding, which remains one of the principal challenges for the modern science.

To address this problem, we employ experimental approaches that combine chemistry with physics and biology, along with theory and computation. The model proteins we study are chemically synthesized in our laboratory. In order to gain the most detailed picture of the folding process, we study folding using a variety of experimental spectroscopic methods. Finally, we process and analyze the folding data, and develop theoretical models for the folding mechanism.

In parallel, we are improving and developing new experimental methods for study of protein folding as well as theoretical approaches for their analysis and interpretation.

Our research is supported by the National Science Foundation CAREER grant

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