Publications (2002–present)

Molecular Biology

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Department of Molecular Biology

University of Wyoming

Department #3944

1000 E. University Ave.

Laramie, WY 82071

Phone: (307) 766-3300

Fax: (307) 766-5098

Email: mbiology@uwyo.edu

Publications (2024–Present)

Owen Funk, Daniel L. Levy*, David S. Fay* (2024). Epidermal cell fusion promotes the transition from an embryonic to a larval transcriptome in C. elegans. biorxiv 2024.05.22.595354; doi: https://doi.org/10.1101/2024.05.22.595354

Shae M. Milne, Philip T. Edeen, David S. Fay* (2024). TAT-1, a phosphatidylserine flippase, affects molting and regulates membrane trafficking in the epidermis of C. elegans. Genetics PMID: 39722491

Shaonil Binti, Philip T. Edeen, and David S. Fay* (2024). Loss of the Na+/K+ cation pump CATP-1 suppresses nekl-associated molting defects. G3 (Bethesda). 2024 Oct 21:jkae244. doi: 10.1093/g3journal/jkae244. PMID: 39428996

Shaonil Binti, Adison G. Linder, Phillip T. Edeen, and David S. Fay* (2024). A conserved protein tyrosine phosphatase, PTPN-22, functions in diverse developmental processes in C. elegans. PLoS Genet. doi: 10.1371/journal.pgen.1011219. eCollection 2024 Aug. PMID: 39173071

Braveen B. Joseph, Naava Naslavsky, Shaonil Binti, Sylvia Conquest, Lexi Robison, Ge Bai, Rafael O. Homer, Barth D. Grant, Steve Caplan and David S. Fay* (2023). Conserved NIMA kinases regulate multiple steps of endocytic trafficking. PLoS Genetics. doi: org/10.1371/journal.pgen.1010741. eCollection 2023 April. PMID: 37099601

Braveen B. Joseph, Philip T. Edeen, Sarina Meadows, Shaonil Binti and David S. Fay* (2022). An unexpected role for the conserved ADAM family metalloprotease ADM-2 in Caenorhabditis elegans molting. PLoS Genetics. 2022 May 31;18(5):e1010249. doi: 10.1371/journal.pgen.1010249. eCollection 2022 May. PMID: 35639786

Shaonil Binti, Rosa Melinda, Phil Edeen, Sam D. Miller, Braveen B. Joseph, and David S. Fay* (2022). A life cycle alteration can correct defects in molting. Dev. Biol. 481:143-156. PMID: 35038442

Stephanie Grimbert, Karina Mastronardi, Ryan Christensen, Christopher Law, K. Zardoui, David S. Fay, and Alisa Piekny (2021). Multi-tissue patterning drives anterior morphogenesis of the C. elegans embryo. Dev. Biol. 471:49-64. PMID: 33309948

Braveen B. Joseph, Yu Wang, Phil Edeen, Vladimir Lažetić, Barth D. Grant and David S. Fay* (2020). Control of clathrin-mediated endocytosis by NIMA family kinases. PLoS Genetics. 2020 Feb 18;16(2):e1008633. doi: 10.1371/journal.pgen.1008633. eCollection 2020 Feb. PMID:32069276

Julian Poush, Nicolas A. Blouin, Kristin R. Di Bona, Vladimir Lažetić, and David S. Fay* (2018). Regulation of germ cell development by ARI/HHARI family ubiquitin ligases. Scientific Reports 2018 Dec 10;8(1):17737. doi: 10.1038/s41598-018-35691-y. PMID: 30531803

Vladimir Lažetić, Braveen B. Joseph, Sarina M. Bernazzani, and David S. Fay* (2018) Actin organization and endocytic trafficking are controlled by a network linking NIMA-related kinases to the CDC-42–SID-3/ACK1 pathway. PLoS Genet. 2018 Apr 2;14(4):e1007313. doi: 10.1371/journal.pgen.1007313. PMID: 29608564

Braveen B. Joseph, Nicolas A. Blouin, and David S. Fay* (2018) Use of a Sibling Subtraction Method (SSM) for Identifying Causal Mutations in C. elegans by Whole-Genome Sequencing. G3: Genes, Genomes, Genetics, 6, 669–678. PMID: 29237702.

Katja K. Dove, Hilary A. Kemp, Kristin Di Bona, Luke J. Milburn, David Camacho, David S. Fay, Dana L. Miller, Rachel E Klevit (2017) Two functionally distinct E2/E3 pairs coordinate sequential ubiquitination of a common substrate in C. elegans development. PNAS, 114, E6576–E6584. PMID: 28739890.

Vladimir Lazetic and David S. Fay (2017). Conserved ankyrin repeat proteins and their NIMA kinase partners regulate extracellular matrix remodeling and intracellular trafficking in Caenorhabditis elegans. Genetics, 205, 273–293. PMID: 27799278

Vladimir Lažetić and David S. Fay* (2017). Molting in C. elegans. Worm, 6(1):e1330246 PMID:28702275

Melissa Kelley, John Yochem, Michael Krieg, Andrea Calixto, Maxwell G. Heiman, Aleksandra Kuzmanov, Vijaykumar Meli, Martin Chalfie, Miriam B. Goodman, Shai Shaham, Alison Frand, and David S. Fay* (2015). FBN-1, a fibrillin-related protein, is required for resistance of the epidermis to mechanical deformation during C. elegans embryogenesis. eLife, Mar 12;4. PMID: 25798732. http://elifesciences.org/content/4/e06565

John Yochem, Vladimir Lazetic, Leslie R. Bell, Lihsia Chen, and David S. Fay* (2015). C. elegans NIMA-related kinases NEKL-2 and NEKL-3 are required for the completion of molting. Dev. Biol. 398, 255-266. PMID: 25523392 ( .pdf )

Aleksandra Kuzmanov, John Yochem and David S. Fay (2014). Analysis of PHA-1 reveals a limited role in pharyngeal development and novel functions in other tissues. Genetics, 198, 259-268. PMID: 25009149 ( .pdf )

Aleksandra Kuzmanov, Evguenia I. Karina, Natalia V. Kirienko, and David S. Fay* (2014) The conserved PBAF nucleosome remodeling complex mediates the response to stress in C. elegans. Mol Cell. Biol. 34, 1121-1135. PMID: 24421384 ( .pdf )

Stanley R.G. Polley, Aleksandra Kuzmanov, Jujaio Kuang, Jonathan Karpel, Vladimir Lazetic, Evguenia I. Karina, Bethany L. Veo, Aleksandra Kuzmanov, David S. Fay* (2014). Implicating SCF complexes in organogenesis in C. elegans, Genetics 196, 211-223. PMID: 24214340 ( .pdf )

David S. Fay* (2013). WormBook Methods: Classical Genetic Methods. The C. elegans Research Community, WormBook, doi/10.1895/wormbook.1.165.1, http://www.wormbook.org. PMID: 24395816

David S. Fay* and Ken Gerow (2013). WormBook Methods: A biologists guide to statistical thinking and analysis. The C. elegans Research Community, WormBook, doi/10.1895/wormbook.1.159.1, http://www.wormbook.org. PMID: 23908055

David S. Fay*, Stanley R.G. Polley, Jujaio Kuang, Aleksandra Kuzmanov, James W. Hazel, Kumaran Mani, Bethany L. Veo, and John Yochem (2012). A regulatory module controlling pharyngeal development and function in C. elegans. Genetics 191, 1367-1380 . ( .pdf )

Michelle Sait, Olga Kamneva, David S. Fay, Natalia V. Kirienko, James Polek, Mimi M. Shirasu-Hiza, Naomi L. Ward (2011). Genomic and Experimental Evidence Suggests that Verrucomicrobium spinosum Interacts with Eukaryotes. Frontiers in Microbiology, 2, 211. ( .pdf )

Natalia V. Kirienko, Kumaran Mani, and David S. Fay (2010). Cancer Models in C. elegans. Developmental Dynamics. 239:1413-1448. ( .pdf )

Natalia V. Kirienko and David S. Fay (2010). SLR-2 and JMJC-1 regulate an evolutionarily-conserved stress-response network. EMBO. J. 29(4):727-739 ( .pdf )

Kumaran Mani and David S. Fay (2009). A Mechanistic Basis for the Coordinated Regulation of Pharyngeal Morphogenesis in C. elegans by LIN-35/Rb and UBC-18-ARI-1. PLoS Genetics. Vol 5 issue 6, e1000510. ( web site)

David S. Fay (2008). Classic genetics goes high tech. Nat. Methods. 5, 863-864. ( .pdf )

Natalia V. Kirienko, John D. K. McEnerney, and David S. Fay (2008). Coordinated regulation of intestinal functions in C. elegans by LIN-35/Rb and SLR-2. PLoS Genetics, Vol 4 issue 4, e1000059. ( web site)

Natalia V. Kirienko and David S. Fay (2007). Transcriptome profiling of the C. elegans Rb ortholog reveals diverse developmental roles. Dev. Biol. 305, 674–684. ( .pdf )

David S. Fay and John Yochem (2007). The SynMuv genes of Caenorhabditis elegans in vulval development and beyond. Dev. Biol. 306, 1–9. ( .pdf )

Saeyoull Cho, Katherine W. Rogers, and David S. Fay (2007). The C. elegans glycopeptide hormone receptor ortholog, FSHR-1, regulates germline differentiation and survival. Curr. Biol. 17, 203–212. ( .pdf )

Aaron M. Bender, Natalia V. Kierienko, Sara K. Olson, B.S. Jeffery D. Esko, and David S. Fay (2007). lin-35/Rb and the CoREST ortholog spr-l coordinately regulate vulval morphogenesis and gonad development in C. elegans. Dev. Biol. 302, 448–462. ( .pdf )

Xiaohui Qiu and David S. Fay (2006). ARI-1, an RBR family ubiquitin ligase, functions with UBC-18 to regulate pharyngeal development in C. elegans. Dev. Biol. 291, 239-252.

David S. Fay et al., (2006) WormBook-Methods; Forward Genetics: Genetic mapping and manipulation. Author/Curator. http://www.wormbook.org/.

David S. Fay. (2005). The cell cycle and development: Lessons from C. elegans. Sem. Cell and Dev. Biol. 16, 297-406. ( .pdf)

Aaron M. Bender, Orion Wells, and David S. Fay. (2004 ). lin-35/Rb and xnp-1/ATR-X function redundantly to control somatic gonad development in C. elegans. Dev. Biol. 273, 335-349. ( .pdf)

Mingxue Cui, David S. Fay and Min Han. (2004). lin-35/Rb cooperates with the SWI/SNF complex to control Caenorhabditis elegans larval development. Genetics 167, 1177-1185. ( .pdf)

David S. Fay, Xiaohui Qiu, Edward Large, Christopher P. Smith, Susan Mango and Bethany L. Johanson. (2004). The coordinate regulation of pharyngeal development in C. elegans by lin-35/Rb, pha-1, and ubc-18. Dev. Biol. 271, 11-25. ( .pdf)

David S. Fay, Edward Large, Min Han, and Monica Darland. (2003) lin-35/Rb and ubc-18, an E2 ubiquitin-conjugating enzyme, function redundantly to control pharyngeal morphogenesis in C. elegans. Development 130: 3319-3330. ( .pdf)

David S. Fay, Sean Keenan, and Min Han (2002). fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C. elegans as revealed by a nonbiased synthetic screen. Genes and Development 16, 503-517. (Cover Article). ( .pdf)