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Chemical and Petroleum Engineering|College of Engineering and Applied Science

Maciej Radosz

Professor of Chemical and Petroleum Engineering
Room 3022, Engineering Building
University of Wyoming
College of Engineering and Applied Science
Department of Chemical & Petroleum Engineering
Dept. 3295
1000 E. University Avenue
Laramie, WY 82071
radosz@uwyo.edu
Phone: 307.766.4926

Soft Materials Laboratory Soft Materials Laboratory

Education:
  • M.S., Cracow University of Technology, Poland
  • Ph.D., Cracow University of Technology, Poland
  • Postdoc, Norwegian University of Science and Technology, 1978-1980
  • Postdoc, Purdue University, 1980-1981

Experience:
  • ExxonMobil Research and Engineering Company, Engineering, 1981-1985
  • ExxonMobil Research and Engineering Company, Corporate Research Science Labs, 1985-1994
  • Rutgers University, Chemical and Biochemical Engineering, Visiting Professor, 1992-1994
  • Louisiana State University, Chemical Engineering, Distinguished Professor and M.F. Gautreaux/Ethyl Corporation Endowed Chair, 1995-2000
  • Louisiana State University, Chemistry, Adjunct Professor
  • University of Wyoming, Chemical and Petroleum Engineering, Professor and Department Head, 2000-2004


Specialization: 

  • Soft materials and biomaterials, drug delivery, polymers, separations, supercritical fluids, equations of state, CO2 capture

 

Recent Projects

  • Self-assembly of block copolymers in compressible solvents, funded by NSF
  • Nano-structured biomaterials for drug and gene delivery, with Y. Shen, funded by NSF, NIH, DoD
  • Carbon Filter Process aimed at carbon capture on carbonaceous sorbents, funded by State of Wyoming and industry
  • Polyolefin fouling, funded by industry

 

Recent Publications
A total of about 300, including 235 peer-reviewed
Over 10,000 citations

  •  Bo Zhang, Xinpeng Ma, Meihua Sui, Edward Van Kirk, William J. Murdoch, Maciej Radosz, Nengming Lin, Youqing Shen;  Guanidinoamidized Linear Polyethyleneimine for Gene Delivery.  Chinese Journal of Polymer Science 2014, submitted. 

235.      Sun, Q.; Sun, X.; Ma, X.; Zhou, Z.; Jin, E.; Zhang, B.; Radosz, M.; et al., Integration of Nanoassembly Functions for an Effective Delivery Cascade for Cancer Drugs. Advanced Materials 2014. DOI: 10.1002/adma.201401554

234.      Wu, Y.; Chen, X.; Radosz, M.; Fan, M., Dong, W.; Zhang, Z.; et al.  Inexpensive calcium-modified potassium carbonate sorbent for CO2. Fuel 2014, 125, 50-56.

233.     Green, J.; Radosz, M.; Shen, Y., Near-Critical Micellization for Nanomedicine: Enhanced Drug Loading, Reduced Burst Release. In Functional Polymers for Nanomedicine, Shen, Y., Ed. Royal Society of Chemistry: London, 2013.

232.     Jin, E.; Zhang, B.; Sun, X.; Zhou, Z.; Ma, X.; Sun, Q.; Tang, J.; Shen, Y.; Van Kirk, E.; Murdoch, W.; Radosz, M., Acid-Active Cell-Penetrating Peptides for in Vivo Tumor-Target Drug Delivery. Journal of the American Chemical Society 2013, 135, (2), 933-940.

231.     Strzelec, K.; Kedzierski, W.; Bereznowski, A.; Janczarek, I.; Bocian, K.; & Radosz, M.,   Salivary cortisol levels in horses and their riders during three-day-events. Bulletin of The Veterinary Institute in Pulawy 2013, 57, (2), 237-241.

230.     Sun, Q.; Radosz, M.; Shen, Y., Rational Design of Translational Nanocarrier. In Functional Polymers for Nanomedicine, Shen, Y., Ed. Royal Society of Chemistry: London, 2013.

229.     Sun, Q.; Wang, J.; Radosz, M.; Shen, Y., Polymer-Based Prodrugs for Cancer Chemotherapy. In Functional Polymers for Nanomedicine, Shen, Y., Ed. Royal Society of Chemistry: London, 2013.

228.     Zhang, B.; Ma, X.; Murdoch, W.; Radosz, M.; Shen, Y., Bioreducible poly(amino amine)s with different branching degrees as gene delivery vectors. Biotechnology and Bioengineering 2013, 110, (3), 990-998.

227.     Zhou, Z.; Ma, X.; Jin, E.; Tang, J.; Sui, M.; Shen, Y.; Van Kirk, E.; Murdoch, W.; Radosz, M., Linear-dendritic drug conjugates forming long-circulating nanorods for cancer-drug delivery. Biomaterials 2013, 34, (22), 5722-5735.

2012

226.     Dutcher, B.; Krutkramelis, K.; Adidharma, H.; Radosz, M., Caron Filter Process for Flue-Gas Carbon Capture on Carbonaceous Sorbents: Field Tests of Steam-Aided Vacuum Swing Adsorption. Energy & Fuels 2012, 26, (4), 2539-2545.

225.     Sun, Q.; Radosz, M.; Shen, Y., Challenges in Design of Translational Nanocarriers. Journal of Controlled Release 2012, 164, 156-169.

224.     Tyrrell, Z.; Shen, Y.; Radosz, M., Multilayered Nanoparticles for Controlled Release of Paclitaxel Formed by Near-Critical Micellization of Triblock Copolymers. Macromolecules 2012, 45, (11), 4809-4817.

2011

223.     Dutcher, B.; Adidharma, H.; Radosz, M., Carbon Filter Process for Flue-Gas Carbon Capture on Carbonaceous Sorbents: Steam-Aided Vacuum Swing Adsorption Option. Industrial & Engineering Chemistry Research 2011, 50, (16), 9696-9703.

222.     Green, J.; Tyrrell, Z.; Radosz, M.; Hong, K.; Mays, J. W., Nanostructure of Solid Precipitates Obtained By Expansion of Polystyrene-block-Polybutadiene Solutions in Near Critical Propane: Block Ration and Micellar Solution Effects. Journal of Physical Chemistry C 2011, 115, (19), 9465-9470.

221.     Hu, X.; Fan, M.; Towler, B. F.; Radosz, M.; Bell, D. A.; Plumb, O. A., Hydrogen Adsorption and Storage. In Coal Gasification and Its Application, 2011; pp 157-245.

220.     Hu, X.; Radosz, M.; Cychosz, K. A.; Thommes, M., CO2-Filling Capacity and Selectivity of Carbon Nanopores: Synthesis, Texture, and Pore-Size Distribution for Quenched-Solid Density Functional Theory (QSDFT). Environmental Science Technology 2011, 45, (16), 7068-7074.

219.     Tyrrell, Z.; Shen, Y.; Radosz, M., Near-Critical Fluid Micellization for High and Efficient Drug Loading: Encapsulation of Paclitaxel into PEG-b-PCL Micelles. Journal of Physical Chemistry C 2011, 115, (24), 11951-11956.

218.     Winoto, W.; Radosz, M., Decompression-Induced Encapsulation of Core-philic Solutes by Block Copolymer Micelles in Compressible Solutions: Polystyrene and Polystyrene-block-polybutadiene in Near-Critical Propane. Macromolecules 2011, 44, (13), 5392-5400.

2010

217.     Fan, M.; Wang, J.; Ettema, R.; Northam, M. A.; Hansen, A. C.; Argyle, M. D.; Shen, Y.; Radosz, M., Application of Green Chemistry in Energy Production. Journal of Physical Chemistry A 2010, 114, (11), 3743.

216.     Green, J.; Tyrrell, Z.; Radosz, M., Micellization of Poly(ethylene glycol)-block-Poly(caprolactone) in Compressible Near Critical Solvents. Journal of Physical Chemistry C 2010, 114, (39), 16082-16086.

215.     Jenczyk, J.; Makrocka-Rydzyk, M.; Wypych, A.; Glowinkowski, S.; Jurga, S.; Radosz, M., The phase structure and molecular dynamics in poly(styrene-b-isoprene) diblock copolymer. Journal of Non-Crystalline Solids 2010, 356, (11-17), 582-588.

214.     Shen, Y.; Zhou, Z.; Sui, M.; Tang, J.; Xu, P.; Van Kirk, E.; Murdoch, W.; Fan, M.; Radosz, M., Charge-reversal polyamidoamin dendrimer for cascade nuclear drug delivery. Nanomedicine 2010, 5, (8), 1205-1217.

213.     Tang, H.; Murphy, C. J.; Zhang, B.; Shen, Y.; Van Kirk, E.; Murdoch, W.; Radosz, M., Curcumin polymers as anticancer conjugates. Biomaterials 2010, 31, (27), 7139-7149.

212.     Tyrrell, Z.; Shen, Y.; Radosz, M., Fabrication of micellar nanoparticles for drug delivery through the self-assembly of block copolymers. Progress in Polymer Science 2010, 35, (9), 1128-1143.

2009

211.     Ma, X.; Tang, J.; Shen, Y.; Fan, M.; Tang, H.; Radosz, M., Facile Synthesis of Polyester Dendrimers from Sequential Click Coupling of Asymmetrical Monomers. Journal of the American Chemical Society 2009, 131, (41), 14795-14803.

210.     Tang, H.; Radosz, M.; Shen, Y., Controlled/"Living" radical polymerization of vinyl acetate. ACS Symposium Series 2009, 1023, (Controlled/Living Radical), 139-157.

209.     Tang, H.; Radosz, M.; Shen, Y., Atom transfer radical polymerization and copolymerization of vinyl acetate catalyzed by copper halide/terpyridine. AIChE Journal 2009, 55, (3), 737-746.

208.     Tang, J.; Shen, Y.; Radosz, M.; Sun, W., Isothermal Carbon Dioxide Sorption in Poly(ionic liquid)s. Industrial & Engineering Chemistry Research 2009, 48, (20), 9113-9118.

207.     Tyrrell, Z.; Winoto, W.; Shen, Y.; Radosz, M., Block Copolymer Micelles Formed in Supercritical Fluid Can Become Water-dispensable Nanoparticles: Poly(ethylene glycol)-block-Poly(ε-caprolactone) in Trifluoromethane. Industrial & Engineering Chemistry Research 2009, 48, (4), 1928-1932.

206.     Winoto, W.; Shen, Y.; Radosz, M.; Hong, K.; Mays, J. W., Deuteration Impact on Micellization Pressure and Cloud Pressure of Polystyrene-block-polybutadiene and Polystyrene-bock-polyisoprene in Compressible Propane. Journal of Physical Chemistry B 2009, 113, (46), 15156-15161.

205.     Winoto, W.; Tan, S. P.; Shen, Y.; Radosz, M.; Hong, K.; Mays, J. W., High-Pressure Micellar Solutions of Polystyrene-block-Polybutadiene and Polystyrene-block-Polyisoprene Solutions in Propane Exhibit Cloud-Pressure Reduction and Distinct Micellization End Points. Macromolecules 2009, 42, (11), 3823-3826.

204.     Winoto, W.; Tan, S. P.; Shen, Y.; Radosz, M.; Hong, K.; Mays, J. W., High-pressure micellar solutions of symmetric and asymmetric styrene-diene diblocks in compressible near-critical solvents: micellization pressures and cloud pressures respond but micellar cloud pressures insensitive to copolymer molecular weight, concentration, and block ratio changes. Macromolecules 2009, 42, (18), 7155-7163.

203.     Winoto, W. R., M.; Hong, K.; Mays, J., Amorphous Polystyrene-block-Polybutadiene and Crystallizable Polystyrene-block-Poly (Hydrogenated Butadiene) in Propane and Propylene - Hydrogenation Effects. Journal of Non-Crystalline Solids 2009, 355, (24-27), 1393-1399.

202.     Zhang, L.; Tang, H.; Tang, J.; Shen, Y.; Meng, L.; Radosz, M.; Arulsamy, N., Pentadentate Copper Halide Complexes Have Higher Catalytic Activity in Atom Transfer Radical Polymerization of Methyl Acrylate than Hexadentate Complexes. Macromolecules 2009, 42, (13), 4531-4538.

201.     Zhou, Z.; Shen, Y.; Tang, J.; Fan, M.; Van Kirk, E.; Murdoch, W.; Radosz, M., Charge-Reversal Drug Conjugate for Targeted Cancer Cell Nuclear Drug Delivery. Advanced Functional Materials 2009, 19, (22), 3580-3589. 


Patents and Recently Published Patent Applications

Poly(ionic liquid)s as new materials for CO2 separation and other applications. U.S. Patent 8,449,652, issued May 28, 2013

Carbon-rich sorbent filters. New Zealand Patent 581989, issued September 3, 2012

Highly active catalyst for atom transfer radical polymerization.  U.S. Patent 7,994,087, issued August 9, 2011

Supercritical Mixed-Solvent Separation of Polymer Mixtures, U.S. Patent 5,264,536

Low-Emission, Ester-Based Stocks for Low-Emission Lubricants, U.S. Patent 5,674,822

Carbon-rich sorbent filters. Australian Patent Application, filed 3/8/2013 Australia 201301370

Poly(ionic liquid)sorbents and membranes for CO2 separation. U.S. Pat. Appl. Publ. (2013), 23 pp. US 2013/0225401 A1

Degradable thermoresponsive poly(ethylene glycol) analogue materials. U.S. Pat. Appl. Publ. (2012), 19 pp. US 2012/0177592 A1

Curcumin-containing polymers and water soluble curcumin derivatives as prodrugs or prodrug carriers.  U.S. Pat. Appl. Publ. (2012), 22 pp. US 2012/0003177 A1

Carbon-rich sorbent filters. U.S. Pat. Appl. Publ. (2010), 17 pp. US 2010/0242728 A1

Processing nanoparticles by micellization of blocky-copolymers in subcritical and supercritical solvents. U.S. Pat. Appl. Publ. (2010), 7 pp. US 2010/0270695 A1

Brominated poly(2,6-diphenyl-1,4-phenylene oxide) and its nanocomposites as membranes for carbon dioxide separations. U.S. Pat. Appl. Publ. (2010), 7 pp. US 2010/0152037 A1

Nanoparticles for cytoplasmic drug delivery to cancer cells. U.S. Pat. Appl. Publ. (2010), 13 pp. US 2010/0203149 A1

Polymers and copolymers of ionic liquids as radio frequency absorbing materials. U.S. Pat. Appl. Publ. (2008), 14 pp. US 2008/0125559 A1

Degradable nanogel for drug delivery.    U.S. Pat. Appl. Publ.  (2007),  8pp.  CODEN: USXXCO US  2007/022416 A1 20070927 CAN 147:371859  AN 2007:1085828   

 (Co-Inventors: Youqing Shen, William Murdoch, Edward Van Kirk, Peisheng Xu, Huadong Tang, et al.)

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