Basile Lab

Analytical Chemistry and Mass Spectrometry

The Basile Research Group at the University of Wyoming centers on Analytical Chemistry with a focus on the application of Mass Spectrometry to analyze a variety of biological and environmental samples.

Specifically, our research is aimed at developing rapid biological sample preparation techniques suitable for proteomic measurements that can be implemented in field-portable instrumentation.  These techniques are based on the use of non-enzymatic steps to lyse/digest biological samples to a stage that is suitable for MS analysis.  Our laboratory pioneered the use of microwave heating for non-enzymatic digestion of proteins at aspartic acid and disulfide bonds and Thermal Degradation/Digestion that reduce digestion times from hours to seconds.

Research conducted by the Basile Group also focuses on the development of broad-spectrum techniques, both methodology and instrumentation, for the analysis of complex mixtures in biological (metabolomics) and environmental (coal) samples.

Find Out More

People, Events and Activities

Contact Information

• Basile Faculty Page
  
• Department of Chemistry
  
• Our laboratory is located in the Physical Sciences Bldg, Room 444 (Online Map|Printable Map)
  
• UW campus parking permit map